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中华损伤与修复杂志(电子版) ›› 2017, Vol. 12 ›› Issue (03) : 203 -206. doi: 10.3877/cma.j.issn.1673-9450.2017.03.010

所属专题: 文献

综述

放射性损伤:类型、症状和机制
陈犹白1, 柴密2, 乌兰哈斯2, Qixu Zhang3, 韩岩2,()   
  1. 1. 100853 北京,解放军总医院整形修复科;77030 休斯敦,美国德克萨斯大学MD安德森肿瘤中心整形科
    2. 100853 北京,解放军总医院整形修复科
    3. 77030 休斯敦,美国德克萨斯大学MD安德森肿瘤中心整形科
  • 收稿日期:2017-03-12 出版日期:2017-06-01
  • 通信作者: 韩岩
  • 基金资助:
    国家自然科学基金面上项目(81272123、81571864)

Radiation-induced injury: classification, manifestation, and mechanism

Youbai Chen1, Mi Chai2, Hasi Wulan2, Qixu Zhang3, Yan Han2,()   

  1. 1. Department of Plastic and Reconstructive Surgery, People′s Liberation Army General Hospital, Beijing 100853, China;Department of Plastic Surgery, University of Texas, MD Anderson Cancer Center, Houston 77030, USA
    2. Department of Plastic and Reconstructive Surgery, People′s Liberation Army General Hospital, Beijing 100853, China
    3. Department of Plastic Surgery, University of Texas, MD Anderson Cancer Center, Houston 77030, USA
  • Received:2017-03-12 Published:2017-06-01
  • Corresponding author: Yan Han
  • About author:
    Corresponding author: Han Yan, Email:
引用本文:

陈犹白, 柴密, 乌兰哈斯, Qixu Zhang, 韩岩. 放射性损伤:类型、症状和机制[J/OL]. 中华损伤与修复杂志(电子版), 2017, 12(03): 203-206.

Youbai Chen, Mi Chai, Hasi Wulan, Qixu Zhang, Yan Han. Radiation-induced injury: classification, manifestation, and mechanism[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2017, 12(03): 203-206.

本文通过检索PubMed和SinoMed中与放射性损伤(RII)相关的文献,总结常见的电离辐射和RII的影响因素,分析RII的分子机制和基因调控,讨论不同细胞周期和肿瘤细胞的放射线易感性,介绍不同组织RII的症状及病理机制,展望干细胞治疗RII的未来方向。

Recent literatures on radiation-induced injury (RII) were searched in PubMed and SinoMed. Common ionizing radiation and factors of RII were summarized. More importantly, the molecular mechanism and gene regulation were analyzed. The radiosusceptibility of normal cell at different stage of cell cycle and cancer cell were discussed. Furthermore, symptoms and pathological mechanism of RII of different organs or tissues were briefly introduced. Finally, the authors also looked into the future of treating RII using stem cell therapy.

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