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中华损伤与修复杂志(电子版) ›› 2022, Vol. 17 ›› Issue (05) : 435 -439. doi: 10.3877/cma.j.issn.1673-9450.2022.05.010

综述

脊柱转移瘤手术并发症研究进展
曹叙勇1, 刘耀升1,()   
  1. 1. 100071 北京,解放军总医院第五医学中心骨科
  • 收稿日期:2022-07-20 出版日期:2022-10-01
  • 通信作者: 刘耀升
  • 基金资助:
    北京市科委首都临床特色课题(z171100001017176)

Research progress of surgical complications of spinal metastasis

Xuyong Cao1, Yaosheng Liu1,()   

  1. 1. Department of Orthopedics, Fifth Medical Center of PLA General Hospital, Beijing 100071, China
  • Received:2022-07-20 Published:2022-10-01
  • Corresponding author: Yaosheng Liu
引用本文:

曹叙勇, 刘耀升. 脊柱转移瘤手术并发症研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2022, 17(05): 435-439.

Xuyong Cao, Yaosheng Liu. Research progress of surgical complications of spinal metastasis[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(05): 435-439.

脊柱转移瘤是恶性肿瘤的严重并发症,随着肿瘤患者生存率改善,脊柱转移瘤发生率不断提升。减压手术联合术后放疗能明显改善患者的功能预后和生存质量,因此与单纯放疗相比,减压手术联合术后放疗已成为脊柱转移瘤患者的优先治疗选择。然而,手术并发症仍是一个严峻的问题。依据并发症出现的时间节点可以分为术中并发症、术后并发症。术中并发症主要包括脊髓神经损伤、脑脊液漏、血管损伤以及周围器官损伤等;术后并发症主要包括内固定失败、手术切口感染、脊柱不稳和假关节形成、肿瘤局部复发以及其他系统性并发症。本综述将对脊柱转移瘤的手术并发症以及相关风险因素进行阐述与介绍,以期为预防与避免脊柱转移瘤手术并发症的发生提供参考依据。

Spinal metastasis is a serious complication of malignant tumors. With the improvement of survival rate, the incidence of spinal metastasis is increasing. Decompressive surgery combined with postoperative radiotherapy can significantly improve the functional prognosis and quality of life of patients, therefore decompressive surgery combined with postoperative radiotherapy has become a priority treatment option for patients with spinal metastasis, as compared with radiotherapy alone. However, surgical complications are still a serious problem. According to the occurrence time of complications, complications can be divided into intraoperative complications and postoperative complications. Intraoperative complications mainly include spinal cord nerve injury, cerebrospinal fluid leakage, vascular injury and peripheral organ injury and so on. Postoperative complications mainly include failure of internal fixation, infection of surgical incision instability, pseudoarthrosis, local recurrence of tumor and other systemic complications. This review will introduce the surgical complications and related risk factors of spinal metastases, in order to provide reference and basis for preventing and avoiding the complications of spinal metastases.

[1]
Macdonald AG, Lynch D, Garbett I, et al. Malignant spinal cord compression[J]. J R Coll Physicians Edinb, 2019, 49(2): 151-156.
[2]
Silva GT, Bergmann A, Thuler LC. Incidence, associated factors, and survival in metastatic spinal cord compression secondary to lung cancer[J]. Spine J, 2015, 15(6): 1263-1269.
[3]
Patchell RA, Tibbs PA, Regine WF, et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial[J]. Lancet, 2005, 366(9486): 643-648.
[4]
Lei M, Li J, Liu Y, et al. Who are the Best Candidates for Decompressive Surgery and Spine Stabilization in Patients With Metastatic Spinal Cord Compression : A New Scoring System[J]. Spine (Phila Pa 1976), 2016, 41(18): 1469-1476.
[5]
雷明星,刘耀升,周诗国,等. 肺癌脊柱转移瘤脊髓压迫后路减压内固定术生存期预测模型的建立[J]. 中华骨与关节外科杂志2015, 8(6): 495-501.
[6]
Paulino Pereira NR, Ogink PT, Groot OQ, et al. Complications and reoperations after surgery for 647 patients with spine metastatic disease[J]. Spine J, 2019, 19(1): 144-156.
[7]
Schuss P, Guresir A, Schneider M, et al. Factors influencing early postoperative complications following surgery for symptomatic spinal metastasis: a single-center series and multivariate analysis[J]. Neurosurg Rev, 2020, 43(1): 211-216.
[8]
Tateiwa D, Oshima K, Nakai T, et al. Clinical outcomes and significant factors in the survival rate after decompression surgery for patients who were non-ambulatory due to spinal metastases[J]. J Orthop Sci, 2019, 24(2): 347-352.
[9]
Bouthors C, Prost S, Court C, et al. Outcomes of surgical treatments of spinal metastases: a prospective study[J]. Support Care Cancer, 2020, 28(5): 2127-2135.
[10]
Krisht KM, Mumert ML, Schmidt MH. Management considerations and strategies to avoid complications associated with the thoracoscopic approach for corpectomy[J]. Neurosurg Focus, 2011, 31(4): E14-E21.
[11]
Pascal-Moussellard H, Broc G, Pointillart V, et al. Complications of vertebral metastasis surgery[J]. Eur Spine J, 1998, 7(6): 438-444.
[12]
Ikard RW. Methods and complications of anterior exposure of the thoracic and lumbar spine[J]. Arch Surg, 2006, 141(10): 1025-1034.
[13]
Kumar N, Tan B, Zaw AS, et al. The role of preoperative vascular embolization in surgery for metastatic spinal tumours[J]. Eur Spine J, 2016, 25(12): 3962-3970.
[14]
Ragel BT, Kan P, Schmidt MH. Blood transfusions after thoracoscopic anterior thoracolumbar vertebrectomy[J]. Acta Neurochir (Wien), 2010, 152(4): 597-603.
[15]
Pedreira R, Abu-Bonsrah N, Karim Ahmed A, et al. Hardware failure in patients with metastatic cancer to the spine[J]. J Clin Neurosci, 2017, 45: 166-171.
[16]
Quraishi NA, Rajabian A, Spencer A, et al. Reoperation rates in the surgical treatment of spinal metastases[J]. Spine J, 2015, 15(3 Suppl): S37-S43.
[17]
Amankulor NM, Xu R, Iorgulescu JB, et al. The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors[J]. Spine J, 2014, 14(9): 1850-1859.
[18]
Kumar N, Patel R, Wadhwa AC, et al. Basic concepts in metal work failure after metastatic spine tumour surgery[J]. Eur Spine J, 2018, 27(4): 806-814.
[19]
Omeis IA, Dhir M, Sciubba DM, et al. Postoperative Surgical Site Infections in Patients Undergoing Spinal Tumor Surgery[J]. Spine, 2011, 36(17): 1410-1419.
[20]
Carl HM, Ahmed AK, Abu-Bonsrah N, et al. Risk factors for wound-related reoperations in patients with metastatic spine tumor[J]. J Neurosurg Spine, 2018, 28(6): 663-668.
[21]
Mesfin A, Sciubba DM, Dea N, et al. Changing the Adverse Event Profile in Metastatic Spine Surgery: An Evidence-Based Approach to Target Wound Complications and Instrumentation Failure[J]. Spine(Phila Pa 1976), 2016, 41(20): S262-S270.
[22]
Igarashi T, Murakami H, Demura S, et al. Risk factors for local recurrence after total en bloc spondylectomy for metastatic spinal tumors: A retrospective study[J]. J Orthop Sci, 2018, 23(3): 459-463.
[23]
Amelot A, Balabaud L, Choi D, et al. Surgery for metastatic spine tumors in the elderly. Advanced age is not a contraindication to surgery![J]. Spine J, 2017, 17(6): 759-767
[24]
Zaw AS, Sonawane D, Maharanjan K, et al. Perioperative blood transfusion: does it influence survival and cancer progression in metastatic spine tumor surgery [J]. Spine J, 2017, 17(3): S18-S19.
[25]
Clausen C, Lönn L, Morgen SS, et al. Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases[J]. Eur Spine J, 2014, 23(8): 1791-1796.
[26]
Paulino Pereira NR, Langerhuizen DW, Janssen SJ, et al. Are perioperative allogeneic blood transfusions associated with 90-days infection after operative treatment for bone metastases [J]. J Surg Oncol, 2016, 114(8): 997-1003.
[27]
Hussain AK, Vig KS, Cheung ZB, et al. The Impact of Metastatic Spinal Tumor Location on 30-Day Perioperative Mortality and Morbidity After Surgical Decompression[J]. Spine (Phila Pa 1976), 2018, 43(11): E648-E655.
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