观察东莞市虎门地区19例创伤弧菌感染的临床特点。

回顾性分析东莞市滨海湾中心医院烧伤整形和手足外科2018年1月至2023年1月收治的创伤弧菌感染患者19例临床资料，观察其临床特点并总结救治经验和教训。

19例创伤弧菌感染多发生于夏秋两季(13/19，68.42%)。患代谢性疾病或肝功能异常者易感(11/19，57.89%)，死亡3例均为痛风患者。19例患者中18例为入院当天创伤弧菌培养阳性(抗生素应用前)，1例为入院第2天创伤弧菌培养阳性，之后细菌培养均未发现创伤弧菌。白细胞数量与中性粒细胞百分比、降钙素原具有相关性(r＝0.972，P＝0.000；r＝0.861，P＝0.006)，白细胞水平随病情改善呈逐步下降趋势。

虎门地区创伤弧菌感染多发生于夏秋两季，患代谢性疾病者易感，痛风患者预后差，对多数抗生素敏感。白细胞和降钙素原是反映病情及转归的良好指标。

To explore the clinical characteristics of 19 cases of Vibrio vulnificus infection in Humen area.

The clinical data of 19 patients with Vibrio vulnificus infection admitted to Burn Plastic & Hand and Foot Surgery, Dongguan Binhai Bay Central Hospital from January 2018 to January 2023 were retrospectively analysed, observed the clinical characteristics and summarized the experience and lessons of treatment.

Vibrio vulnificus infection mostly occured in summer and autumn (13/19, 68.42%). The patients with metabolic disease or abnormal liver function were susceptible (11/19, 57.89%), and the prognosis of gout patients was relatively worse, the three deaths were all gout patients. There were 18 positive cases in bacterial culture of Vibrio vulnificus before the application of antibiotics on the day of admission, one positive case was found one day later. Afterwards, no Vibrio vulnificus was found in bacterial culture. The number of white blood cells were closely related to the percentage of neutrophils and the level of procalcitonin (r=0.972, P=0.000; r=0.861, P=0.006). The white blood cell levels gradually decreased along with the condition improved.

The infection of Vibrio vulnificus in Humen area mostly occurs in summer and autumn. Patients with metabolic diseases are more susceptible, and gout patients have a poor prognosis. Vibrio vulnificus is sensitive to most antibiotics. The white blood cell and procalcitonin are good indicators for the severity and prognosis.