切换至 "中华医学电子期刊资源库"

中华损伤与修复杂志(电子版) ›› 2026, Vol. 21 ›› Issue (04) : 247 -252. doi: 10.3877/cma.j.issn.1673-9450.2026.04.002

皮瓣移植与修复重建

内窥镜辅助下采用钟摆形背阔肌肌皮瓣修复乳腺癌术后乳房缺损的临床效果
田晨阳, 官浩, 胡大海, 计鹏, 杨云舒, 刘博, 郑朝()   
  1. 710032 西安,空军军医大学第一附属医院烧伤与皮肤外科
  • 收稿日期:2025-12-02 出版日期:2026-08-01
  • 通信作者: 郑朝
  • 基金资助:
    国家自然科学基金(82302809); 西安市科技计划项目(24YXYJ0015)

Clinical efficacy of endoscope-assisted pendulum-shaped latissimus dorsi myocutaneous flap for reconstruction of breast defects after surgery in breast cancer patients

Chenyang Tian, Hao Guan, DaHai Hu, Peng Ji, Yunshu Yang, Bo Liu, Chao Zheng()   

  1. Department of Burns and Cutaneous Surgery,the First Affiliated Hospital of Air Force Medical University,Xi'an 710032,China
  • Received:2025-12-02 Published:2026-08-01
  • Corresponding author: Chao Zheng
引用本文:

田晨阳, 官浩, 胡大海, 计鹏, 杨云舒, 刘博, 郑朝. 内窥镜辅助下采用钟摆形背阔肌肌皮瓣修复乳腺癌术后乳房缺损的临床效果[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(04): 247-252.

Chenyang Tian, Hao Guan, DaHai Hu, Peng Ji, Yunshu Yang, Bo Liu, Chao Zheng. Clinical efficacy of endoscope-assisted pendulum-shaped latissimus dorsi myocutaneous flap for reconstruction of breast defects after surgery in breast cancer patients[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2026, 21(04): 247-252.

目的

探讨内窥镜辅助下切取钟摆形背阔肌肌皮瓣修复乳腺癌术后乳房缺损的临床效果。

方法

2021年6月至2024年2月,空军军医大学第一附属医院烧伤与皮肤外科收治符合入选标准的乳腺癌术后乳房缺损患者9例,均为女性,年龄13~51岁。乳腺癌均未复发。其中假体植入后皮肤缺损4例,乳腺癌切除后乳房缺损5例。乳房皮肤软组织缺损面积为7.0 cm×4.0 cm~11.0 cm×7.5 cm。对患者进行清创后,于内窥镜辅助下切取钟摆形背阔肌肌皮瓣修复创面,供区创面一期缝合。术后常规行抗炎、抗凝、防止血管痉挛治疗,卧床制动,密切观察皮瓣血运情况。术后3 d拔除引流管,12~14 d拆线。随访观察创面愈合情况、乳房形态及肿瘤是否复发。

结果

9例患者术后皮瓣均成活良好。术后随访6~12个月,随访期间未见乳腺癌复发患者。4例假体外露患者创面均已完全愈合,未出现假体再次外露。5例乳房缺损患者创面愈合良好,其中3例患侧乳房形态与健侧乳房存在一定差异。供区切口均愈合良好,仅1例出现明显瘢痕增生,经激光治疗后显著改善。供区横行切口形成的线性瘢痕可通过穿衣遮盖,外观影响较小。

结论

内窥镜辅助下切取钟摆形背阔肌肌皮瓣修复乳腺癌术后乳房缺损,具有术中操作简便、供区美观、有利于假体保留并预防假体再次外露等优势,是一种安全且有效的手术方法。

Objective

To explore the clinical effect of the pendulum-shaped latissimus dorsi myocutaneous flap harvested with endoscopic assistance for repairing breast defects after surgery in breast cancer patients.

Methods

From June 2021 to February 2024,9 patients with breast defects after surgery who met the inclusion criteria were admitted to the Department of Burns and Cutaneous Surgery of the First Affiliated Hospital of Air Force Medical University. All patients were female,aged 13 to 51 years. The breast cancer had not recurred. Among them,4 cases had skin defects after breast implant placement,5 cases had breast defects after breast cancer resection. The area of breast skin soft tissue defect ranged from 7.0 cm × 4.0 cm to 11.0 cm × 7.5 cm. All patients underwent debridement and then received repair with a pendulum-shaped latissimus dorsi myocutaneous flap harvested with endoscopic assistance,and the donor area wounds were sutured in one stage. Postoperative anti-inflammatory,anticoagulation,and prevention of vascular spasm treatments were performed,and bed rest was required. Postoperatively,the blood supply of the flap was closely observed. The drainage tube was removed on postoperative day 3, and the sutures were removed 12-14 days after the operation. Observed the wound healing,breast shape,and whether the tumor recurred during follow-up.

Results

The flaps of all 9 patients survived well after the operation. The postoperative follow-up period was 6 to 12 months. During the follow-up period,no cases of breast cancer recurrence were observed. For the 4 patients with exposed implants,the wounds had completely healed,and no implants re-exposure occurred. Among the 5 patients with breast defects,the wounds healed well,but there were certain differences in shape between the reconstructed and the contralateral breast in 3 cases. The incisions in the donor area healed well,and only 1 case had obvious scar hyperplasia,which was significantly improved after laser treatment. The linear scars formed by the transverse incision in the donor area could be covered by clothing,and the impact on appearance was slight.

Conclusion

The pendulum-shaped latissimus dorsi myocutaneous flap harvested with endoscopic assistance for repairing breast defects after surgery in breast cancer patients offers several advantages,including simple intraoperative operation,favorable aesthetic outcomes at the donor area,facilitation of implant retention,and prevention of implant re-exposure. It is a safe and effective surgical technique.

图1 采用内窥镜辅助下钟摆形背阔肌肌皮瓣修复乳腺癌术后假体外露创面。A示右乳内下象限假体外露;B示根据创面大小设计钟摆形背阔肌肌皮瓣;C示术中皮瓣修复后即刻效果;D示术后2周拆线,右乳皮瓣效果;E示术后1年随访,右乳皮瓣效果;F示术后1年随访,右乳皮瓣支撑效果;G示术后1年随访,供区横行切口瘢痕情况;H示术后1年随访,供区瘢痕可通过穿衣遮盖
图2 采用内窥镜辅助下钟摆形背阔肌肌皮瓣修复乳腺癌术后乳房缺损创面。A示右乳外上象限瘢痕窦道溃疡牵拉乳头乳晕复合体移位;B示根据创面大小设计钟摆形背阔肌肌皮瓣;C示术中皮瓣修复后即刻效果;D示术后2周拆线,右乳皮瓣效果;E示术后1年随访,正位右乳皮瓣效果;F示术后1年随访,侧位右乳皮瓣效果;G示术后1年随访,供区横行切口瘢痕情况;H示术后1年随访,供区瘢痕可通过穿衣遮盖
[1]
Sung HFerlay JSiegel RL,et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin202171(3): 209-249. DOI:10.3322/caac.21660.
[2]
Kim ZMin SYYoon CS,et al. The basic facts of korean breast cancer in 2012: results from a Nationwide Survey and Breast Cancer Registry Database[J]. J Breast Cancer201518(2):103-111. DOI:10.4048/jbc.2015.18.2.103.
[3]
Vorstenbosch JMcCarthy CMShamsunder MG,et al. Smooth versus textured implant breast reconstruction: patient-reported outcomes and complications[J]. Plast Reconstr Surg2021148(5):959-967. DOI:10.1097/PRS.0000000000008411.
[4]
Kang MJHong HKEo PS,et al. Surgical strategies for partial breast reconstruction in medial-located breast cancer: a 12-year experience[J]. J Breast Cancer202326(1):35-45. DOI:10.4048/jbc.2023.26.e8.
[5]
Moran MSSchnitt SJGiuliano AE,et al. Society of surgical oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages Ⅰ and Ⅱ invasive breast cancer[J]. J Clin Oncol201432(14): 1507-1515. DOI:10.1200/JCO.2013.53.3935.
[6]
梁燕,姜军. 乳腺癌的区域外科治疗[J]. 中国普外基础与临床杂志201926(12): 1398-1402. DOI:10.7507/1007-9424.201909026.
[7]
马建勋,夏有辰,李比,等. 乳腺癌改良根治术后即刻乳房重建的方式选择[J]. 北京大学学报(医学版)202355(4): 612-618. DOI:10.19723/j.issn.1671-167X.2023.04.007.
[8]
Zhang BSong QZhang B,et al. A 10-year (1999-2008) retrospective multi-center study of breast cancer surgical management in various geographic areas of China[J]. Breast201322(5): 676-681. DOI:10.1016/j.breast2013.01.004.
[9]
Chen JHuang NXue J,et al. Current status of breast reconstruction in Southern China: a 15 year,single institutional experience of 20,551 breast cancer patients[J]. Medicine(Baltimore)201594(34): e1399. DOI:10.1097/MD.0000000000001339.
[10]
石雪芹,郑朝,胡大海,等. 标准化方案在乳腺癌术后游离大网膜即刻乳房重建术中的应用[J]. 西北国防医学杂志201940(12): 727-731. DOI:10.16021/j.cnki.1007-8622.2019.12.001.
[11]
李南林,郑朝,李纪鹏,等. 游离大网膜移植即刻再造乳房7例[J]. 中华乳腺病杂志(电子版)201610(4): 210-214. DOI:10.3877/cma.j.issn.1674-0807.2016.04.004.
[12]
吴娟,郭丝锦,郝遥,等. 乳腺癌术后Ⅰ期假体植入乳房重建术患者术后感染预测模型构建及防控策略[J]. 中国消毒学杂志202542(1): 38-41. DOI:10.11726/j.issn.1001-7658.2025.01.013.
[13]
林冬颜,程光,何昭好,等. 乳腺癌术后Ⅱ期假体植入患者围手术期感染的相关因素分析[J]. 中华医院感染学杂志201929(1): 106-109. DOI:10.11816/cn.ni.2019-174138.
[14]
Zingaretti NPiana MBattellino L,et al. Pre-pectoral breast reconstruction: surgical and patient-reported outcomes of two-stages vs single-stage implant-based breast reconstruction[J]. Aesthetic Plast Surg202448(9): 1759-1772. DOI:10.1007/s00266-023-03601-x.
[15]
Perez-Tejada JLabaka AVegas O,et al. Anxiety and depression after breast cancer: the predictive role of monoamine levels[J]. Eur J Oncol Nurs202152:101953. DOI:10.1016/j.ejon.2021.101953.
[16]
Lee SJung YBae Y. Immediate chest wall reconstruction using an external oblique myocutaneous flap for large skin defects after mastectomy in advanced or recurrent breast cancer patients: a single center experience[J]. J Surg Oncol2018117(2):124-129. DOI:10.1002/jso.24830.
[17]
Zhang XHuang YMu D. Efficiency in DIEP flap breast reconstruction: the real benefit of computed tomographic angiography imaging[J]. Plast Reconstr Surg2021148(2):301e-302e. DOI:10.1097/PRS.0000000000008107.
[18]
谢庆平,穆籣,刘元波,等. 腹壁下动脉穿支皮瓣专家共识[J]. 中华显微外科杂志202043(5):417-423. DOI:10.3760/cma.j.cn441206-20200826-00331.
[19]
Escandón JMEscandón LAhmed A,et al. Breast reconstruction using the latissimus dorsi flap and immediate fat transfer (LIFT): a systematic review and meta-analysis[J]. J Plast Reconstr Aesthet Surg202275(11):4106-4116. DOI:10.1016/j.bjps.2022.08.025.
[20]
Wang QChen SRXie HT,et al. Immediate breast reconstruction with latissimus dorsi flap and implant: the innovation of flap design and transfer[J]. Aesthetic Plast Surg202549(13):3680-3687. DOI:10.1007/s00266-025-04740-z.
[21]
D'Alessandro GSMunhoz AMTakeuchi FM,et al. Immediate breast reconstruction with latissimus dorsi myocutaneous flap and silicone implant followed by adjuvant radiotherapy for breast cancer[J]. Ann Plast Surg202492(6):625-634. DOI:10.1097/SAP.0000000000003882.
[22]
侯宏义,谢松涛,曹涛,等. 在内镜辅助下经小切口切取游离背阔肌肌瓣修复四肢深度创面的临床效果[J]. 中华烧伤与创面修复杂志202541(8):768-774. DOI:10.3760/cma.j.cn501225-20240929-00361.
[23]
Ma JXLi BXia YC,et al. Latissimus dorsi muscle flap transfer through endoscopic approach combined with the implant after tissue expansion for breast reconstruction of mastectomy patients[J]. BMC Surg202222(1):10. DOI:10.1186/s12893-021-01464-0.
[24]
冯玉,罗桂林,梁法清,等. 腔镜与开放手术获取背阔肌用于乳房重建的比较研究[J]. 中国普外基础与临床杂志202532(3):293-299. DOI:10.7507/1007-9424.202411035.
[25]
Sood REasow JMKonopka G,et al. Latissimus dorsi flap in breast reconstruction: recent innovations in the workhorse flap[J]. Cancer Control201825(1):1073274817744638. DOI:10.1177/1073274817744638.
[26]
Escandón JMNazerali RCiudad P,et al. Minimally invasive harvest of the latissimus dorsi flap for breast reconstruction: a systematic review[J]. Int J Med Robot202218(6):e2446. DOI:10.1002/rcs.2446.
[1] 王硕, 郑新宇. 乳腺癌术后同侧乳腺肿瘤复发的病理学认知与处理[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 133-137.
[2] 丁彩霞, 曲景辉, 裴英宏, 李静娜, 郑晓瑜, 徐岭植, 李思思. 基于RNA结合蛋白基因表达特征的乳腺癌预后预测模型构建及评价分析[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 138-147.
[3] 王美衡, 李杰, 陈策实, 许超汉. 乳腺癌串联重复表型的识别及分子功能特征分析[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 148-155.
[4] 范遥, 黄玉娥, 杨森果, 丁华, 张黔, 刘蜀. 线粒体基质导入因子23在三阴性乳腺癌中的表达及其作用机制[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 156-162.
[5] 王静坤, 计美妮, 王玉凤, 宣浩军. 真空辅助乳腺活检与空芯针穿刺活检在乳腺癌诊断中的对比研究[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 163-168.
[6] 程妹, 金亚彬, 马丁瑞, 程昊, 詹玉莲, 周丹. 基于深度学习的MRI图像分析在乳腺癌诊疗中的应用[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 169-173.
[7] 宁海洋, 武春慧, 刘妍, 许慧娟, 高婷婷, 李炘正. 吲哚菁绿在乳腺癌外科诊疗中的应用[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 174-178.
[8] 黄家骏, 周奕延, 王斐然, 何志贤. 系统性红斑狼疮与乳腺癌关系的研究进展[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 179-183.
[9] 闫文修, 党受琴, 穆亚男, 曹文荣. 乳腺滤泡树突细胞肉瘤一例[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 184-186.
[10] 魏欣, 张雁瑞, 刘远欢, 杨怡晖, 汤红平. 乳腺原发性黏液表皮样癌一例[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 190-192.
[11] 樊蕊蕊, 高杰. 乳腺黏液性囊腺癌一例[J/OL]. 中华乳腺病杂志(电子版), 2026, 20(03): 193-195.
[12] 张耀林, 蔡兴博, 王腾, 杨曦, 李朝波, 吕黎明, 徐永清. 应用可吸收螺钉联合股方肌骨瓣移植术治疗股骨头坏死[J/OL]. 中华关节外科杂志(电子版), 2026, 20(03): 275-282.
[13] 徐敏骅, 方圆, 朱丽均, 杨瑜麟. 女性参加宫颈癌和乳腺癌筛查意愿及其影响因素研究[J/OL]. 中华妇幼临床医学杂志(电子版), 2026, 22(03): 250-258.
[14] 张慧君, 曹彤瑜, 代强, 蒋徽豪, 杜伟力, 覃凤均, 陈辉, 沈余明. 应用带腹壁下血管的脐旁穿支皮瓣修复大腿或腹股沟区放射性溃疡的临床效果[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(04): 241-246.
[15] 袁强, 范慈勃, 韩丽丽, 陈光, 陈纲, 赵锁. 融合病理图像与报告的多模态模型用于乳腺癌预后预测[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(04): 374-378.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?