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中华损伤与修复杂志(电子版) ›› 2016, Vol. 11 ›› Issue (06) : 465 -468. doi: 10.3877/cma.j.issn.1673-9450.2016.06.015

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综述

烧冲复合伤时肺泡Ⅱ型上皮细胞损伤的机制及防治研究进展
刘锐1, 王树明2,()   
  1. 1. 150036 哈尔滨,黑龙江省医院烧伤科
    2. 150040 哈尔滨,黑龙江中医药大学附属第一医院急诊科
  • 收稿日期:2016-11-12 出版日期:2016-12-01
  • 通信作者: 王树明
  • 基金资助:
    基金资助:全军"十二五"后勤科研计划课题资助项目(CKJ12J027); 哈尔滨市科技局科技创新人才研究专项资金项目(2016RAQXJ159, 2015RAQYJ078)

Advancement of study on the mechanisms and treatment of injured typeⅡ alveolar epithelial cell in burn-blast combined injury

Rui Liu1, Shuming Wang2,()   

  1. 1. Department of Burns, Heilongjiang Provincial Hospital, Harbin 150036, China
    2. Department of Emergency Medicine, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China
  • Received:2016-11-12 Published:2016-12-01
  • Corresponding author: Shuming Wang
  • About author:
    Corresponding author: Wang Shuming, Email:
引用本文:

刘锐, 王树明. 烧冲复合伤时肺泡Ⅱ型上皮细胞损伤的机制及防治研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2016, 11(06): 465-468.

Rui Liu, Shuming Wang. Advancement of study on the mechanisms and treatment of injured typeⅡ alveolar epithelial cell in burn-blast combined injury[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2016, 11(06): 465-468.

烧冲复合伤是平战时常见的致命性损伤,它较单纯的烧伤或冲击伤更严重,其救治困难,病死率高。临床资料表明,肺是烧冲复合伤最易受损的脏器,也是影响烧冲复合伤患者预后的重要因素,因此,肺损伤的治疗是治疗烧伤复合伤的关键。肺泡Ⅱ型上皮细胞(AECⅡ)损伤在肺损伤中起重要的作用。近年来有关烧冲复合伤时AECⅡ损伤的机制及干预措施的研究逐渐成为外科领域的研究热点之一,本文现就有关烧冲复合伤时AECⅡ损伤的机制及干预措施的研究综述如下。

Burn-blast combined injury is common traumatic injury in both wars and daily life. It′s more serious than burn or blast injury, the treatment of burn-blast combined injury is more difficult, and it’s mortality is higher. Clinical data has shown that lung is the main target organ in the burn-blast combined injury. The degree of lung injury is closely related to the prognosis of patients with burn-blast combined injury. So the treatment of lung injury is the key factor for the treatment of burn-blast combined injury. Pre-clinical research has shown that the alveolar type Ⅱ epithelial cell (AEC Ⅱ) plays an important role in the development of the occurrence of lung injury during burn-blast combined injury.In recent years, the mechanism and and treatment of injured AEC Ⅱ in burn-blast combined injury has become one of the hotspots in the field of surgery. In this review, the mechanisms and treatment of injured ACE Ⅱ in burn-blast combined injury are discussed.

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