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中华损伤与修复杂志(电子版) ›› 2019, Vol. 14 ›› Issue (01) : 63 -66. doi: 10.3877/cma.j.issn.1673-9450.2019.01.013

所属专题: 文献

综述

重度烧伤后高代谢特征及临床治疗新进展
舒付婷1, 罗鹏飞1, 纪世召1, 夏照帆1,()   
  1. 1. 200433 上海,海军军医大学第一附属医院烧创伤中心
  • 收稿日期:2018-12-10 出版日期:2019-02-01
  • 通信作者: 夏照帆
  • 基金资助:
    国家自然科学基金(81772076, 81120108015); 十三五科技计划(AWS14C001, 201502028, AWS11J008); 国家973计划项目(2012CB518100)

The characteristics and new progress in clinical treatment of hypermetabolism after severe burns

Futing Shu1, Pengfei Luo1, Shizhao Ji1, Zhaofan Xia1,()   

  1. 1. Burn trauma center, First Affiliated Hospital of Naval Military Medical University, Shanghai 200433, China
  • Received:2018-12-10 Published:2019-02-01
  • Corresponding author: Zhaofan Xia
  • About author:
    Corresponding author: Xia Zhaofan, Email:
引用本文:

舒付婷, 罗鹏飞, 纪世召, 夏照帆. 重度烧伤后高代谢特征及临床治疗新进展[J/OL]. 中华损伤与修复杂志(电子版), 2019, 14(01): 63-66.

Futing Shu, Pengfei Luo, Shizhao Ji, Zhaofan Xia. The characteristics and new progress in clinical treatment of hypermetabolism after severe burns[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2019, 14(01): 63-66.

重度烧伤后机体应激导致神经内分泌调节紊乱,涉及机体长时间高强度的代谢反应、难以纠正的蛋白质代谢紊乱、长期的顽固高血糖及胰岛素低敏性等,不仅增加了营养支持和治疗困难,而且常常会增加机体感染概率、延迟组织修复,导致严重烧伤患者多器官功能障碍的风险增加。因此深入研究重度烧伤后高代谢,探索其有效的治疗方案一直是临床研究的热点。本文通过回顾近年来重度烧伤高代谢的特征及治疗进展,以期为临床救治提供切实可行的方法。

After severe burns, the body′s stress leads to neuroendocrine modulation disorder, involving long-term high-intensity metabolic reactions, incorrigible protein metabolism disorders, long-range stubborn hyperglycemia and insulin hyposensitivity, which not only increase the difficulties of the nutrition support and treatment, but also increase the chance of infection and delay tissue repair, leading to an increased risk of multiple organ dysfunction in severe burns. Therefore, hypermetabolism after severe burns and its effective treatment have always been a hot issue in clinical research. This article reviews the characteristics and the new treatment progress of severe burns in recent years, in order to provide a practical method for clinical treatment.

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