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中华损伤与修复杂志(电子版) ›› 2019, Vol. 14 ›› Issue (05) : 388 -392. doi: 10.3877/cma.j.issn.1673-9450.2019.05.014

所属专题: 文献

综述

细胞悬液移植技术在创面修复中的研究与应用进展
姜耀男1, 肖仕初1,()   
  1. 1. 200433 海军军医大学第一附属医院烧伤外科
  • 收稿日期:2019-08-08 出版日期:2019-10-01
  • 通信作者: 肖仕初
  • 基金资助:
    国家自然科学基金面上项目(81871559)

Progress in research and application of cell suspension transplantation technology in wound repair

Yaonan Jiang1, Shichu Xiao1,()   

  1. 1. Department of Burns Surgery, First Affiliated Hospital, Naval Military Medical University, Shanghai 200433, China
  • Received:2019-08-08 Published:2019-10-01
  • Corresponding author: Shichu Xiao
  • About author:
    Corresponding author: Xiao Shichu, Email:
引用本文:

姜耀男, 肖仕初. 细胞悬液移植技术在创面修复中的研究与应用进展[J/OL]. 中华损伤与修复杂志(电子版), 2019, 14(05): 388-392.

Yaonan Jiang, Shichu Xiao. Progress in research and application of cell suspension transplantation technology in wound repair[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2019, 14(05): 388-392.

由各类因素所导致的急性、慢性、难愈性及医源性创面在临床上十分常见,常严重影响患者的生活质量并增加患者经济及社会医疗负担。随着细胞悬液移植相关的制备技术和载体材料研究趋渐成熟,其降低供皮区面积、治疗效果明确等优点使得自体/异体细胞应用于皮肤创面的治疗研究成为近年来创面修复临床研究的热点之一。但细胞悬液制备技术和载体技术目前尚无统一标准且部分技术尚未进行严格临床研究验证,仍需进行进一步临床研究明确其疗效及适应证。本文从细胞悬液的制备、移植及临床应用3个方面,对细胞悬液移植技术在创面修复方面的研究与应用进行归纳整理,以期为临床及科研工作者提供参考依据。

Acute, chronic, refractory and iatrogenic wounds caused by various factors are very commonn in the clinic, often seriously affecting the quality of life of patients and increasing the burden of economy and social medical resources. With the progress of preparation technology and carrier materials related to cell suspension transplantation, it has the advantages of reducing the area of donor site and clear therapeutic effect, making the treatment of autologous/allogeneic cells applied to skin wounds become the clinical research hotspots of wound repair in recent years. However, there is no uniform standard for cell suspension preparation technology and carrier technology, and some technologies have not been verified by rigorous clinical research. Further clinical research is needed to clarify its efficacy and indications. This article reviewes the research and application of cell suspension transplantation technology in wound repair on the 3 aspects of preparation, transplantation and clinical application of cell suspension, in order to provide reference for clinicians and scientific researchers.

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