切换至 "中华医学电子期刊资源库"

中华损伤与修复杂志(电子版) ›› 2020, Vol. 15 ›› Issue (04) : 264 -267. doi: 10.3877/cma.j.issn.1673-9450.2020.04.006

所属专题: 文献 指南共识

指南与共识

瘢痕癌性溃疡诊断与治疗专家共识(2020年版)
张家平1,(), 江旭品1   
  1. 1. 陆军军医大学(第三军医大学)第一附属医院
  • 收稿日期:2020-07-12 出版日期:2020-08-01
  • 通信作者: 张家平

Expert consensus on diagnosis and treatment of Marjolin ulcer (2020 version)

Jiaping Zhang1,(), Xupin Jiang1   

  1. 1. First Affiliated Hospital of Army Medical University (Third Military Medical University)
  • Received:2020-07-12 Published:2020-08-01
  • Corresponding author: Jiaping Zhang
  • About author:

    Proof Writing:

    Proof Writing:

    Corresponding author: Zhang Jiaping, 400038 Chongqing, State Key Laboratory of Trauma, Burn and Combined Injury, Department of Plastic and Aesthetic Surgery, First Affiliated Hospital of Army Medical University (Third Military Medical University), Email: ;
    Huang Yuesheng, 518020 Shenzhen, Department of Wound Repair, Institute of Wound Repair, Shenzhen People′s Hospital, First Affiliated Hospital of Southern University of Science and Technology, Second Clinical Medical College of Jinan University, Email:
引用本文:

张家平, 江旭品. 瘢痕癌性溃疡诊断与治疗专家共识(2020年版)[J/OL]. 中华损伤与修复杂志(电子版), 2020, 15(04): 264-267.

Jiaping Zhang, Xupin Jiang. Expert consensus on diagnosis and treatment of Marjolin ulcer (2020 version)[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2020, 15(04): 264-267.

瘢痕癌,又被称为马氏溃疡,往往是在瘢痕溃疡的基础上恶变而成,其临床表现为溃疡长期不能愈合。瘢痕癌的致病因素与发生机制尚不十分清楚,但瘢痕反复破溃、糜烂、合并感染等慢性刺激在其病理发展中具有重要意义。目前,有关瘢痕癌的诊疗方案尚未形成统一认识。本文以国内外文献为基础,以全国相关领域专家的临床经验与观点为主要依据,在瘢痕癌性溃疡的病因、病理、临床表现、诊断与鉴别诊断、预防和治疗等方面汇集形成专家共识,为瘢痕癌性溃疡的防治提供参考。

Scar carcinoma, also named as Marjolin ulcer, is commonly derived from the malignant transformation of scar ulcer with its non-healing as the main clinic manifestation. Although the factors and mechanisms of scar carcinoma are not very clear, chronic stimulations such as repeated rupture, erosion and infection of scars play an important role in its pathogenesis. Currently, no consensus on the diagnosis and treatment of scar carcinoma has been developed. Based on the literature and the clinical experience and viewpoints of experts, we developed a consensus regarding on the etiology, pathology, clinical manifestation, diagnosis, prevention and treatment of scar carcinoma, so as to provide helpful reference for its prevention and treatment in clinic.

[1]
Lindelöf B, Krynitz B, Granath F, et al. Burn injuries and skin cancer: a population- based cohort study[J]. Acta Derm Venereol, 2008, 88(1): 20-22.
[2]
Copcu E. Marjolin′s ulcer: a preventable complication of burns[J]. Plast Reconstr Surg, 2009, 124(1): 156e-164e.
[3]
Kowal-Vern A, Criswell BK. Burn scar neoplasms: A literature review and statistical analysis[J]. Burns, 2005, 31(4): 403-413.
[4]
邱丙森. 鳞状细胞癌[M]// 杨国亮,王侠生. 现代皮肤病学. 上海:上海医科大学出版社,1996: 945-975.
[5]
Kasse AA, Betel E, Dem A, et al. Cancers in the scars of thermal burns (apropos of 67 cases)[J]. Dakar Med, 1999, 44(2): 206-210.
[6]
Guenther N, Menenakos C, Braumann C, et al. Squamous cell carcinoma arising on a skin graft 64 years after primary injury[J]. Dermatol Online J, 2007, 13(2): 27.
[7]
Fleming MD, Hunt JL, Purdue GF, et al. Marjolin′s ulcer: a review and reevaluation of a difficult problem[J]. J Burn Care Rehabil, 1990, 11(5): 460-469.
[8]
Trent JT, Kirsner RS. Wounds and malignancy[J]. Adv Skin Wound Care, 2003, 16(1): 31-34.
[9]
O′Byrne KJ, Dalgleish AG. Chronic immune activation and inflammation as the cause of malignancy[J]. Br J Cancer, 2001, 85(4): 473-483.
[10]
刘梅,赵琰,何春涤,等. 皮肤瘢痕癌45例回顾性分析[J]. 中国美容医学,2010, 19(4): 540-542.
[11]
Aydoğdu E, Yildirim S, Aköz T. Is surgery an effective and adequate treatment in advanced marjolin′ s ulcer?[J]. Burns, 2005, 31(4): 421-431.
[12]
Sawhney S, Jain R, Kakaria A, et al. Marjolin′s ulcer: radiographic and magnetic resonance appearances in two cases[J]. Sultan Qaboos Univ Med J, 2009, 9(2): 162-166.
[13]
梁伟强,张金明,潘淑娟,等. 烧伤后瘢痕癌七例的临床分析[J/CD]. 中华临床医师杂志(电子版), 2011, 5(6): 1776-1778.
[14]
Huang CY, Feng CH, Hsiao YC, et al. Burn scar carcinoma[J]. J Dermatolog Treat, 2010, 21(6): 350-356.
[15]
李晖,武斌,陈晓泉. 瘢痕癌临床治疗分析[J]. 现代肿瘤医学,2008, 16(9): 1553-1554.
[16]
张鲜英,刘毅,肖斌,等. 皮肤鳞状细胞癌的外科治疗[J]. 临床肿瘤学杂志,2012, 17(12): 1105-1107.
[17]
谢尔凡,黎鳌. 烧伤瘢痕癌国外进展[J]. 中华整形烧伤外科杂志,1993, 9(6): 430-432.
[18]
汤培,李金树,黄道强,等. 烧伤瘢痕癌治疗分析[J]. 中国医师进修杂志,2006, 29(30): 31-32.
[19]
Ozek C, Cankayali R, Bilkay U, et al. Marjolin′s ulcers arising in burn scars[J]. J Burn Care Rehabil, 2001, 22(6): 384-389.
[20]
LeBoeuf NR, Schmults CD. Update on the management of high-risk squamous cell carcinoma[J]. Semin Cutan Med Surg, 2011, 30(1): 26-34.
[21]
Pekarek B, Buck S, Osher L. A Comprehensive Review on Marjolin′s Ulcers: Diagnosis and Treatment[J]. J Am Coll Clin Wound Spec, 2011, 3(3): 60-64.
[22]
龙忠恒,谢卫国. 瘢痕癌研究进展[J]. 中华烧伤杂志,2014, 30(6): 495-499.
[23]
Edwards MJ, Hirsch RM, Broadwater JR, et al. Squamous cell carcinoma arising in previously burned or irradiated skin[J]. Arch Surg, 1989, 124(1): 115-117.
[1] . 多发伤病历与诊断:专家共识意见(2023版)[J/OL]. 中华危重症医学杂志(电子版), 2024, 17(01): 0-.
[2] 章宇潇, 杨凡, 毛萌. 《生长减缓婴幼儿的追赶性生长:指导普通临床医师的专家共识(2023版)》解读[J/OL]. 中华妇幼临床医学杂志(电子版), 2024, 20(04): 361-366.
[3] 天津市天津医院, 中国医师协会骨科医师分会肩肘外科学组, 国际矫形与创伤外科学会(SICOT)中国部肩肘外科委员会, 中国医疗保健国际交流促进会骨科学分会肩肘外科学部. 老年肱骨近端骨折诊疗策略中国专家共识(2024年版)[J/OL]. 中华肩肘外科电子杂志, 2024, 12(03): 193-204.
[4] 中国医师协会骨科医师分会肩肘外科学组. 桡骨头骨折诊疗中国专家共识(2024版)[J/OL]. 中华肩肘外科电子杂志, 2024, 12(02): 97-102.
[5] 郁凯, 闵先军. 胸锁关节脱位的诊治现状[J/OL]. 中华肩肘外科电子杂志, 2024, 12(01): 10-13.
[6] 中国医药教育协会肩肘运动医学专业委员会. 肩关节前向不稳手术治疗中国专家共识[J/OL]. 中华肩肘外科电子杂志, 2024, 12(01): 1-9.
[7] 中国医师协会神经外科医师分会神经电生理监测学组, 中国研究型医院学会临床神经电生理专业委员会. 颅内外血管搭桥术中神经电生理监测中国专家共识(2024版)[J/OL]. 中华脑科疾病与康复杂志(电子版), 2024, 14(02): 65-72.
[8] 安亚楠, 王端然, 郭甜甜, 武希润. 幽门螺杆菌阴性胃黏膜相关淋巴组织淋巴瘤的研究进展[J/OL]. 中华消化病与影像杂志(电子版), 2024, 14(03): 268-274.
[9] 静脉淋巴功能不全临床专家共识编写组. 静脉淋巴功能不全临床专家共识[J/OL]. 中华临床医师杂志(电子版), 2023, 17(06): 630-638.
[10] 胡琴, 莫伟, 中国研究型医院学会出血专业委员会, 中国出血中心联盟护理专家委员会. 失血性休克急救护理专家共识[J/OL]. 中华介入放射学电子杂志, 2024, 12(03): 193-199.
[11] 黄淑萍, 龚蓓, 申铁梅, 杨丹莉, 陈秀梅, 李国琪, 李星, 麦爱欢, 钟冰, 广东省护士协会心血管疾病护理分会, 南方心血管护理联盟. 心房颤动患者介入手术围术期护理专家共识[J/OL]. 中华介入放射学电子杂志, 2024, 12(01): 1-9.
[12] 中国医师协会心血管内科医师分会结构性心脏病学组, 苏州工业园区东方华夏心管健康研究院. 三尖瓣反流经导管治疗的中国专家共识[J/OL]. 中华心脏与心律电子杂志, 2024, 12(03): 129-139.
[13] 唐东方, 沈晓咏, 张辉标, 茅腾, 孙益峰, 成兴华, 张慧君, 殷正昕, 奚俊杰, 高佳妮, 万紫微, 胡学飞, 罗清泉, 陈晓峰, 李鹤成, 李志刚, 陈昶, 高文. 胸外科肺切除术后患者远程管理专家共识[J/OL]. 中华胸部外科电子杂志, 2024, 11(03): 143-150.
[14] 中国抗癌协会食管癌专业委员会. 机器人辅助食管切除术中国临床专家共识(2023版)[J/OL]. 中华胸部外科电子杂志, 2024, 11(01): 1-15.
[15] 中国医师协会外科医师分会肥胖代谢病综合管理与护理专家工作组, 中国医师协会外科医师分会肥胖和代谢病外科专家工作组, 中国肥胖代谢外科研究协作组. 肥胖代谢外科医学科普中国专家共识(2024 版)[J/OL]. 中华肥胖与代谢病电子杂志, 2024, 10(04): 227-234.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?