切换至 "中华医学电子期刊资源库"

中华损伤与修复杂志(电子版) ›› 2023, Vol. 18 ›› Issue (02) : 104 -108. doi: 10.3877/cma.j.issn.1673-9450.2023.02.003

论著

对糖尿病足溃疡诱因与发生部位的临床观察
雷霞1, 李炳辉1, 王晓蓉1, 张丽娟1, 刘慧真1, 王卉1, 李恭驰2,()   
  1. 1. 430077 武汉,华中科技大学同济医学院附属梨园医院创面修复中心 湖北省慢性创面及糖尿病足医学临床研究中心
    2. 430022 武汉,华中科技大学同济医学院附属协和医院手外科
  • 收稿日期:2023-02-15 出版日期:2023-04-01
  • 通信作者: 李恭驰
  • 基金资助:
    国家自然科学基金青年科学基金项目(81801922); 国家重大疾病多学科合作诊疗能力建设项目(国卫办医函【2019】542号); 湖北省慢性创面及糖尿病医学临床研究中心资助项目(2018BCC340); 湖北省自然科学基金面上项目(2018CFB756)

Clinical observation on predisposing factors and recurrence sites of diabetic foot ulcer

Xia Lei1, Binghui Li1, Xiaorong Wang1, Lijuan Zhang1, Huizhen Liu1, Hui Wang1, Gongchi Li2,()   

  1. 1. Wound Repair Center, Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Hubei Provincial Clinical Research Center of Chronic Wound and Diabetic Foot Medicine, Wuhan 430077, China
    2. Department of Hand Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2023-02-15 Published:2023-04-01
  • Corresponding author: Gongchi Li
引用本文:

雷霞, 李炳辉, 王晓蓉, 张丽娟, 刘慧真, 王卉, 李恭驰. 对糖尿病足溃疡诱因与发生部位的临床观察[J/OL]. 中华损伤与修复杂志(电子版), 2023, 18(02): 104-108.

Xia Lei, Binghui Li, Xiaorong Wang, Lijuan Zhang, Huizhen Liu, Hui Wang, Gongchi Li. Clinical observation on predisposing factors and recurrence sites of diabetic foot ulcer[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2023, 18(02): 104-108.

目的

通过对糖尿病足溃疡诱因与部位的观察为糖尿病足的防控提供依据。

方法

回顾性分析2019年1月至2021年9月华中科技大学同济医学院附属梨园医院创面修复中心收治的230例糖尿病足住院患者的病历资料。收集信息包括患者性别、年龄、居住地、基础疾病、起始发病时是否合并其他疾病、足部溃疡的诱因和部位等情况。数据比较采用χ2检验和Kruskal-Wallis H检验。

结果

(1)由于日常生活及保健行为引起足部溃疡112例,占48.70%;无明确诱因出现溃疡69例,占30.00%;由于皮肤瘙痒、干燥皲裂、水肿、鸡眼等并发症引起49例,占21.30%。患者足溃疡多为复发(178例,占77.39%),其中由不适当的日常生活及保健行为导致的足溃疡复发为98例,占42.61%,足溃疡的诱因对复发的影响大于初发,差异有统计学意义(χ2=12.759,P<0.05)。(2)230例糖尿病足溃疡患者中,复发溃疡患者中多数发病部位为足背(119例,51.74%),其次为足底(40例,占17.39%),足背足底同时存在19例,占8.26%;复发溃疡患者多数发病部位为足背,初发与复发溃疡发病部位比较,差异有统计学意义(χ2=12.349,P<0.05)。(3)由于不适当的日常生活及保健行为引起溃疡的112例患者中77例患者发生在足背,占33.48%;不同溃疡部位与诱因比较,差异有统计学意义(χ2=25.934,P<0.001)。(4)198例(86.09%)溃疡发生于前足,其次21例(9.13%)发生于后足,溃疡发生于两个区域及以上8例(3.48%),少数发生于中足,仅为3例(1.30%);比较溃疡的发病部位和发病位置,溃疡多发生于前足的足背处,差异有统计学意义(χ2=23.530,P<0.05)。

结论

糖尿病足溃疡的发生多为复发,复发多位于前足,且足背多于足底,复发诱因多为不适当的日常生活及保健行为,为糖尿病足复发的预防提供依据。

Objective

To study the inducement and location of diabetes foot ulcer, it provide a basis for the prevention and control of diabetes foot.

Methods

Data of 230 inpatients with diabetic foot admitted to wound Repair Center of Liyuan Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology from January 2019 to September 2021 were retrospectively analyzed. Collected the information includes the patient′s gender, age, place of residence, underlying diseases, whether other diseases were present at the time of onset, the cause and location of foot ulcers, and risk factors. Data were compared by χ2 test and Kruskal-Wallis H test.

Results

(1) 112 cases of foot ulcer caused by daily life and health care behavior, accounting for 48.70% of the total number; there were 69 cases of ulcers without obvious inducements, accounting for 30.00%; 49 cases (21.30%) were caused by itching, dry chapped skin, edema, corns and other complications. Foot ulcers in 178 cases were recurrent, accounted for 77.39%, in which 98 cases caused by inadequate health and daily life behavior, accounting for 42.61%. The inducement of foot ulcers had a greater impact on recurrence than initial onset, the difference was statistically significant (χ2=12.759, P< 0.05). (2) Among the 230 patients with diabetic foot ulcer, 119 cases (51.74%) of the patients with recurrent ulcer were the dorsum of the foot, followed by 40 cases (17.39%) of the plantar, 19 cases (8.26%) of the dorsum and plantar. The majority of patients with recurrent ulcers suffered from the dorsum of the foot, there was statistically significant difference in the location of onset between initial and recurrent ulcers (χ2=12.349, P< 0.05). (3) 112 cases were caused by inappropriate daily life and health care behavior, and 77 cases (33.48%) occurred in the dorsum of the foot. Compared different ulcer site with incentive, the difference was statistically significant (χ2=25.934, P<0.001). (4)198 cases (86.09%) of ulcers occurred on the forefoot, followed by 21 cases (9.13%) of the hind foot, 8 cases (3.48%) in two or more areas, only 3 cases of patients′ ulcers occurred in the midfoot, accounting for 1.30%. Comparing the incidence site and location of ulcers, ulcers often occured at the dorsum of the forefoot, with a statistically significant difference (χ2=23.530, P<0.05).

Conclusion

Diabetes foot ulcer is more recurrent, the recurrence of diabetes foot ulcer is mostly located in the forefoot, and the dorsum of the foot is more than the sole of the foot. The inducement of recurrence is mostly inappropriate daily life and health care behavior, which provides a basis for the prevention of diabetes foot recurrence.

表1 230例糖尿病足溃疡患者基本情况
表2 230例糖尿病足溃疡诱因对复发和初发影响的比较[例(%)]
表3 230例糖尿病足溃疡发病部位与溃疡初发/复发比较[例(%)]
表4 230例糖尿病足溃疡发病部位与诱因的比较[例(%)]
表5 230例糖尿病足溃疡发病部位与发病位置比较[例(%)]
[1]
中华医学会糖尿病学分会,中华医学会感染病学分会,中华医学会组织修复与再生分会. 中国糖尿病足防治指南(2019版)(Ⅰ)[J]. 中华糖尿病杂志201911(2):92-93.
[2]
Wang D, Ouyang J, Zhou P, et al. A novel low-cost wireless footwear system for monitoring diabetic foot patients[J]. IEEE Trans Biomed Circuits Syst, 202115(1):43-54.
[3]
Neville RF, Kayssi A, Buescher T, et al. The diabetic foot[J]. Curr Probl Surg, 201653(9):408-437.
[4]
Fu XL, Ding H, Miao WW, et al. Global recurrence rates in diabetic foot ulcers: a systematic review and meta-analysis[J]. Diabetes Metab Res Rev, 201935(6):e3160.
[5]
Vahwere BM, Ssebuufu R, Namatovu A, et al. Factors associated with severity and anatomical distribution of diabetic foot ulcer in Uganda: a multicenter cross-sectional study[J]. BMC Public Health, 202323(1):463.
[6]
Oyibo SO, Jude EB, Tarawneh I, et al. The effects of ulcer size and site, patient′s age, sex and type and duration of diabetes on the outcome of diabetic foot ulcers[J]. Diabet Med, 200118(2):133-138.
[7]
Orneholm H, Apelqvist J, Larsson J, et al. Recurrent and other new foot ulcers after healed plantar forefoot diabetic ulcer[J]. Wound Repair Regen, 201725(2):309-315.
[8]
Richard JL, Schuldiner S. Epidemiology of diabetic foot problems[J]. Rev Med Interne, 200829 (Suppl 2):S222-S230.
[9]
Yang W, Lu J, Weng J, et al. Prevalence of diabetes among men and women in China[J]. N Engl J Med, 2010362(12):1090-1101.
[10]
Huang ZH, Li S Q, Kou Y, et al. Risk factors for the recurrence of diabetic foot ulcers among diabetic patients: a meta-analysis[J]. Int Wound J, 201916(6):1373-1382.
[11]
龚洪平,任妍,查盼盼,等. 初发与复发性糖尿病足溃疡临床特征分析[J]. 四川大学学报(医学版), 202253(6):969-975.
[12]
Guo Q, Ying G, Jing O, et al. Influencing factors for the recurrence of diabetic foot ulcers: a meta-analysis[J]. Int Wound J, 2022.
[13]
Miller DR, Enoch S, Blow M, et al. Effectiveness of a new brand of stock 'diabetic’ shoes to protect against diabetic foot ulcer relapse. a prospective cohort study[J]. Diabet Med, 200421(6):646-648.
[14]
邹新华,陈洪平,李炳辉. 糖尿病足部的减负治疗[J/CD]. 中华损伤与修复杂志(电子版), 20127(2):189-190.
[15]
Rosinha P, Saraiva M, Ferreira L, et al. A retrospective cohort study on diabetic foot disease: ascertainment of ulcer locations by age group[J]. Cureus, 202214(8):e28189.
[16]
李萍. 住院糖尿病足患者Texas分级及溃疡发生部位的相关危险因素分析[D]. 山东大学,2019.
[17]
姜臻宇. 糖尿病足患者流行病学调查及其截肢的相关危险因素分析[D]. 南昌大学,2020.
[18]
高素文,李炳辉,胡映月,等. 足病师干预对糖尿病足溃疡发生率的影响[J]. 感染、炎症、修复201920(1):32-35.
[19]
康慨,朱伟. 老年糖尿病患者糖尿病足诱因及预防[J]. 中国社区医师202137(10):27-28.
[20]
Zhong A, Li G, Wang D, et al. The risks and external effects of diabetic foot ulcer on diabetic patients: a hospital-based survey in Wuhan area, China[J]. Wound Repair Regen, 201725(5):858-863.
[21]
王秀红,李炳辉,孙奕,等. 基层医院建立糖尿病足工作室模式的探讨[J]. 感染、炎症、修复201920(4):244-246.
[1] 明昊, 肖迎聪, 巨艳, 宋宏萍. 乳腺癌风险预测模型的研究现状[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(05): 287-291.
[2] 庄燕, 戴林峰, 张海东, 陈秋华, 聂清芳. 脓毒症患者早期生存影响因素及Cox 风险预测模型构建[J/OL]. 中华危重症医学杂志(电子版), 2024, 17(05): 372-378.
[3] 黄鸿初, 黄美容, 温丽红. 血液系统恶性肿瘤患者化疗后粒细胞缺乏感染的危险因素和风险预测模型[J/OL]. 中华实验和临床感染病杂志(电子版), 2024, 18(05): 285-292.
[4] 罗文斌, 韩玮. 胰腺癌患者首次化疗后中重度骨髓抑制的相关危险因素分析及预测模型构建[J/OL]. 中华普通外科学文献(电子版), 2024, 18(05): 357-362.
[5] 贺斌, 马晋峰. 胃癌脾门淋巴结转移危险因素[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 694-699.
[6] 黄俊龙, 刘柏隆, 罗瑞翔, 李晓阳, 李文双, 柳政, 陈嘉良, 周祥福. 联合盆底彩超数据和临床资料探讨压力性尿失禁的危险因素[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(04): 323-330.
[7] 林凯, 潘勇, 赵高平, 杨春. 造口还纳术后切口疝的危险因素分析与预防策略[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 634-638.
[8] 杨闯, 马雪. 腹壁疝术后感染的危险因素分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 693-696.
[9] 周艳, 李盈, 周小兵, 程发辉, 何恒正. 不同类型补片联合Nissen 胃底折叠术修补食管裂孔疝的疗效及复发潜在危险因素[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(05): 528-533.
[10] 张伟伟, 陈启, 翁和语, 黄亮. 随机森林模型预测T1 期结直肠癌淋巴结转移的初步研究[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(05): 389-393.
[11] 司楠, 孙洪涛. 创伤性脑损伤后肾功能障碍危险因素的研究进展[J/OL]. 中华脑科疾病与康复杂志(电子版), 2024, 14(05): 300-305.
[12] 颜世锐, 熊辉. 感染性心内膜炎合并急性肾损伤患者的危险因素探索及死亡风险预测[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 618-624.
[13] 李文哲, 王毅, 崔建, 郑启航, 王靖彦, 于湘友. 新疆维吾尔自治区重症患者急性肾功能异常的危险因素分析[J/OL]. 中华卫生应急电子杂志, 2024, 10(05): 269-276.
[14] 刘志超, 胡风云, 温春丽. 山西省脑卒中危险因素与地域的相关性分析[J/OL]. 中华脑血管病杂志(电子版), 2024, 18(05): 424-433.
[15] 曹亚丽, 高雨萌, 张英谦, 李博, 杜军保, 金红芳. 儿童坐位不耐受的临床进展[J/OL]. 中华脑血管病杂志(电子版), 2024, 18(05): 510-515.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?