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中华损伤与修复杂志(电子版) ›› 2017, Vol. 12 ›› Issue (01) : 46 -51. doi: 10.3877/cma.j.issn.1673-9450.2017.01.008

所属专题: 经典病例 文献

论著

富血小板血浆治疗深部胸骨切口感染一例并文献回顾
褚万立1, 郝岱峰1,(), 赵景峰1, 冯光1, 李涛1, 张海军1, 李善友1, 张新健1, 陈泽群1, 赵帆1   
  1. 1. 100048 北京,解放军总医院第一附属医院烧伤整形科三病区暨创口修复中心
  • 收稿日期:2016-11-10 出版日期:2017-02-01
  • 通信作者: 郝岱峰
  • 基金资助:
    解放军总医院临床科研扶持基金(三〇四专项)(2015FC-ZZCB-3041); 首都临床特色应用研究专项课题(Z141107002514167); 首都卫生发展科研专项课题(首发2014-2-5024); 全军后勤科研计划重点项目(BWS14J049)

Platelet rich plasma in the treatment of deep sternal wound infection: case report and literature review

Wanli Chu1, Daifeng Hao1,(), Jingfeng Zhao1, Guang Feng1, Tao Li1, Haijun Zhang1, Shanyou Li1, Xinjian Zhang1, Zequn Chen1, Fan Zhao1   

  1. 1. Department of Burns and Plastic Surgery NO.3, Center of Wound Healing, the First Hospital Affiliated to the People′s Liberation Army General Hospital, Beijing 100048, China
  • Received:2016-11-10 Published:2017-02-01
  • Corresponding author: Daifeng Hao
  • About author:
    Corresponding author: Hao Daifeng, Email:
引用本文:

褚万立, 郝岱峰, 赵景峰, 冯光, 李涛, 张海军, 李善友, 张新健, 陈泽群, 赵帆. 富血小板血浆治疗深部胸骨切口感染一例并文献回顾[J]. 中华损伤与修复杂志(电子版), 2017, 12(01): 46-51.

Wanli Chu, Daifeng Hao, Jingfeng Zhao, Guang Feng, Tao Li, Haijun Zhang, Shanyou Li, Xinjian Zhang, Zequn Chen, Fan Zhao. Platelet rich plasma in the treatment of deep sternal wound infection: case report and literature review[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2017, 12(01): 46-51.

目的

探讨富血小板血浆治疗开胸术后胸骨切口感染的临床疗效。

方法

报道1例使用富血小板血浆成功治疗深部胸骨切口感染的诊疗经过,并以"胸骨切口感染、胸骨感染、纵隔炎、胸骨切开术、胸外科手术和富血小板血浆"为检索词检索中国知网、万方数据库和PubMed相关文献并分析。

结果

患者女,60岁,开胸术后切口不愈3周,诊断为深部胸骨切口感染,使用富血小板血浆治疗6周后胸骨窦道封闭,创面愈合。检索到富血小板血浆治疗胸骨切口感染的相关文献5篇,研究结果提示富血小板血浆可能是预防和治疗胸骨切口感染的有效方法。

结论

富血小板血浆是防治胸骨切口感染的方法之一,也有待进一步应用和研究。

Objective

To investigate the effect of platelet rich plasma in the treatment of sternal wound infection after sternotomy.

Methods

One case of deep sternal wound infection was reported which had been successfully treated with platelet rich plasma and related literatures with "sternal wound infection, sternal infection, mediastinitis, mediastinal infection, sternotomy, thoracic surgery and platelet rich plasma" were reviewed as searching terms in CNKI, Wanfang Data and PubMed.

Results

A 60 year-old female patient was admitted because of sternal wound remaining nonunion for 3 weeks after median sternotomy and was diagnosised as deep sternal wound infection. The wound was treated with platelet rich plasma and healed within 6 weeks accompanied by totally sternal closure. Five literatures with respect to platelet rich plasma in treatment for sternal wound infection were retrieved and prompts platelet rich plasma maybe an effective method for sternal wound infection.

Conclusions

Platelet rich plasma is an alternative treatment for sternal wound infection and it is essential to make further study and investigation.

图1 患者女,60岁,因冠心病行冠状动脉旁路移植术,术后胸部见切口瘢痕、破溃创面及窦道,经清创,填充PRP凝胶及负压封闭引流治疗,创面愈合
表1 PRP治疗胸骨切口感染的相关文献
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