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中华损伤与修复杂志(电子版) ›› 2017, Vol. 12 ›› Issue (04) : 298 -302. doi: 10.3877/cma.j.issn.1673-9450.2017.04.011

所属专题: 文献

综述

A型肉毒毒素的临床研究进展
姜烨容1, 霍然1,()   
  1. 1. 250021 济南,山东大学附属省立医院烧伤整形外科
  • 收稿日期:2017-02-16 出版日期:2017-08-01
  • 通信作者: 霍然
  • 基金资助:
    山东省重点研发计划项目(2016GGB14374)

Clinical progress of type A botulinum toxin

Yerong Jiang1, Ran Huo1,()   

  1. 1. Department of Burns and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China
  • Received:2017-02-16 Published:2017-08-01
  • Corresponding author: Ran Huo
  • About author:
    Corresponding author: Huo Ran, Email:
引用本文:

姜烨容, 霍然. A型肉毒毒素的临床研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2017, 12(04): 298-302.

Yerong Jiang, Ran Huo. Clinical progress of type A botulinum toxin[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2017, 12(04): 298-302.

A型肉毒毒素作为一种嗜神经毒素,主要作用于神经肌肉接头,抑制乙酰胆碱的释放而使靶肌肉松弛。其麻痹肌肉的作用被广泛应用于各个领域。研究发现,其对钾离子、P物质等的释放均有调控作用,这启示大家A型肉毒毒素有更多的应用价值待发现。本文查阅近年来国内外A型肉毒毒素的研究与应用的新动态,着重分析A型肉毒毒素新应用和新发现,旨在为A型肉毒毒素的进一步应用提供指导。

As a kind of neurotropic toxin, type A botulinum toxin mainly acts on the neuromuscular junctions, and inhibits acetylcholine release to make the target muscle relax. It is widely used in various fields because of the function of muscular paralysis. Studies have shown that botulinum toxin has played an important role in the release of K+ , substance P and so on, which enlighten us it has more application value to be found. This article reviews the recent developments in the research and application of type A botulinum toxin at home and abroad, and focuses on the new application and new discoveries of it, which aims to provide guidance for the further application of botulinum toxin.

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