毁损性创面由于其损伤范围广、损伤程度深，并发症、合并症多，修复十分困难，致残率、截肢率、致死率极高，一直以来是外科修复的难点和重点。本文重点就毁损性创面的定义、伤情判断、损害控制理论治疗毁损性创面的应用、各部位创面修复、功能重建、截肢与保肢、多学科合作、负压封闭引流技术在毁损性创面治疗中的特殊作用等方面做了详尽的介绍。随着现代外科技术的不断进步，毁损性创面的修复与重建得到了飞速的发展，但仍有许多不足和遗憾，需要借助现代高科技技术、智能化技术、信息化技术等在毁损性创面修复中发挥更大的作用，以期创面的完美修复。

Because of the wide range of injuries, deep degree of injuries, many complications, it is very difficult to repair the damaged wounds. The disability rate, amputation rate and mortality rate are very high. It has always been the difficulty and focus of surgical repair. This article focuses on the definition of destructive wounds, the judgment of injury condition, the application of damage control theory in the treatment of destructive wounds, the repair of wounds in various parts, functional reconstruction, amputation and limb salvage, multidisciplinary cooperation, and the special role of vacuum sealing drainage in the treatment of destructive wounds. With the continuous progress of modern surgical technology, the repair and reconstruction of damaged wounds have developed rapidly, but there are still many shortcomings and regrets. It is necessary to use modern high-tech technology, intelligent technology and information technology to play a greater role in the repair of destructive wounds in order to perfect the repair of wound.