| [1] |
Masson D, Tschopp J. A family of serine esterases in lytic granules of cytolytic T lymphocytes[J]. Cell, 1987, 49(5): 679-685.
|
| [2] |
Waugh SM, Harris JL, Fletterick R, et al. The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity[J]. Nat Struct Biol, 2000, 7(9): 762-765.
|
| [3] |
Boivin WA, Cooper DM, Hiebert PR, et al. Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma[J]. Lab Invest, 2009, 89(11): 1195-1220.
|
| [4] |
Van Damme P, Maurer-Stroh S, Plasman K, et al. Analysis of protein processing by N-terminal proteomics reveals novel species-specific substrate determinants of granzyme B orthologs[J]. Mol Cell Proteomics, 2009, 8(2): 258-272.
|
| [5] |
Vahedi F, Fraleigh N, Vlasschaert C, et al. Human granzymes: related but far apart[J]. Med Hypotheses, 2014, 83(6): 688-693.
|
| [6] |
Turner CT, Hiroyasu S, Granville DJ. Granzyme B as a therapeutic target for wound healing[J]. Expert Opin Ther Targets, 2019, 23(9): 745-754.
|
| [7] |
Zeglinski MR, Granville DJ. Granzymes in cardiovascular injury and disease[J]. Cell Signal, 2020, 76: 109804.
|
| [8] |
Kurschus FC, Kleinschmidt M, Fellows E, et al. Killing of target cells by redirected granzyme B in the absence of perforin[J]. FEBS Lett, 2004, 562(1/3): 87-92.
|
| [9] |
Bao CX, Chen HX, Mou XJ, et al. GZMB gene silencing confers protection against synovial tissue hyperplasia and articular cartilage tissue injury in rheumatoid arthritis through the MAPK signaling pathway[J]. Biomed Pharmacother, 2018, 103: 346-354.
|
| [10] |
Hendel A, Hsu I, Granville DJ. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability[J]. Lab Invest, 2014, 94(7): 716-725.
|
| [11] |
Shen Y, Cheng F, Sharma M, et al. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis[J]. Am J Pathol, 2016, 186(1): 87-100.
|
| [12] |
张天宇，SHEN Steve, 杨琳. 颗粒酶B在慢性鼓膜穿孔炎症损伤修复中的应用[J]. 中国眼耳鼻喉科杂志，2016, 16(1): 7-9, 15.
|
| [13] |
Hiebert PR, Wu D, Granville DJ. Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice[J]. Cell Death Differ, 2013, 20(10): 1404-1414.
|
| [14] |
Ewen CL, Kane KP, Bleackley RC. A quarter century of granzymes[J]. Cell Death Differ, 2012, 19(1): 28-35.
|
| [15] |
Sanad EF, Hamdy NM, El-Etriby AK, et al. Peripheral leucocytes and tissue gene expression of granzyme B/perforin system and serpinB9: Impact on inflammation and insulin resistance in coronary atherosclerosis[J]. Diabetes Res Clin Pract, 2017, 131: 132-141.
|
| [16] |
Hu X, Zhong Y, Lambers TT, et al. Anti-inflammatory activity of extensively hydrolyzed casein is mediated by granzyme B[J]. Inflamm Res, 2019, 68(8): 715-722.
|
| [17] |
Garzón-Tituaña M, Arias MA, Sierra-Monzón JL, et al. The Multifaceted Function of Granzymes in Sepsis: Some Facts and a Lot to Discover[J]. Front Immunol, 2020, 11: 1054.
|
| [18] |
Wang L, Jiang S, Xiao L, et al. Inhibition of granzyme B activity blocks inflammation induced by lipopolysaccharide through regulation of endoplasmic reticulum stress signaling in NK92 cells[J]. Mol Med Rep, 2018, 18(1): 580-586.
|
| [19] |
Kono H, Karmarkar D, Iwakura Y, et al. Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death[J]. J Immunol, 2010, 184(8): 4470-4478.
|
| [20] |
Afonina IS, Tynan GA, Logue SE, et al. Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1alpha[J]. Mol Cell, 2011, 44(2): 265-278.
|
| [21] |
Akeda T, Yamanaka K, Tsuda K, et al. CD8+ T cell granzyme B activates keratinocyte endogenous IL-18[J]. Arch Dermatol Res, 2014, 306(2): 125-130.
|
| [22] |
Xiao H, Li H, Wang JJ, et al. IL-18 cleavage triggers cardiac inflammation and fibrosis upon beta-adrenergic insult[J]. Eur Heart J, 2018, 39(1): 60-69.
|
| [23] |
Zhang LM, Zhang J, Zhang Y, et al. Interleukin-18 binding protein attenuates lipopolysaccharide-induced acute lung injury in mice via suppression NF-kappaB and activation Nrf2 pathway[J]. Biochem Biophys Res Commun, 2018, 505(3): 837-842.
|
| [24] |
Pilkington SM, Barron MJ, Watson R, et al. Aged human skin accumulates mast cells with altered functionality that localize to macrophages and vasoactive intestinal peptide-positive nerve fibres[J]. Br J Dermatol, 2019, 180(4): 849-858.
|
| [25] |
Campos TM, Novais FO, Saldanha M, et al. Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis[J]. J Infect Dis, 2020, 221(6): 973-982.
|
| [26] |
Qiao J, Zhou M, Li Z, et al. Elevated serum granzyme B levels are associated with disease activity and joint damage in patients with rheumatoid arthritis[J]. J Int Med Res, 2020, 48(11): 300060520962954.
|
| [27] |
Jackson JR, Seed MP, Kircher CH, et al. The codependence of angiogenesis and chronic inflammation[J]. FASEB J, 1997, 11(6): 457-465.
|
| [28] |
Hendel A, Granville DJ. Granzyme B cleavage of fibronectin disrupts endothelial cell adhesion, migration and capillary tube formation[J]. Matrix Biol, 2013, 32(1): 14-22.
|
| [29] |
Nagy JA, Dvorak AM, Dvorak HF. VEGF-A and the induction of pathological angiogenesis[J]. Annu Rev Pathol, 2007, 2: 251-275.
|
| [30] |
Chamberlain CM, Ang LS, Boivin WA, et al. Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm[J]. Am J Pathol, 2010, 176(2): 1038-1049.
|
| [31] |
Gross CC, Meyer C, Bhatia U, et al. CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome[J]. Nat Commun, 2019, 10(1): 5779.
|
| [32] |
Matsubara JA, Tian Y, Cui JZ, et al. Retinal Distribution and Extracellular Activity of Granzyme B: A Serine Protease That Degrades Retinal Pigment Epithelial Tight Junctions and Extracellular Matrix Proteins[J]. Front Immunol, 2020, 11: 574.
|
| [33] |
Mulligan-Kehoe MJ, Drinane MC, Mollmark J, et al. Antiangiogenic plasma activity in patients with systemic sclerosis[J]. Arthritis Rheum, 2007, 56(10): 3448-3458.
|
| [34] |
Buzza MS, Zamurs L, Sun J, et al. Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin[J]. J Biol Chem, 2005, 280(25): 23549-23558.
|
| [35] |
Perl M, Denk S, Kalbitz M, et al. Granzyme B: a new crossroad of complement and apoptosis[J]. Adv Exp Med Biol, 2012, 946: 135-146.
|
| [36] |
Prakash MD, Munoz MA, Jain R, et al. Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling[J]. Immunity, 2014, 41(6): 960-972.
|
| [37] |
Merkulova Y, Shen Y, Parkinson LG, et al. Granzyme B inhibits keratinocyte migration by disrupting epidermal growth factor receptor (EGFR)-mediated signaling[J]. Biol Chem, 2016, 397(9): 883-895.
|
| [38] |
Turner CT, Zeglinski MR, Richardson KC, et al. Granzyme B Contributes to Barrier Dysfunction in Oxazolone-Induced Skin Inflammation through E-Cadherin and FLG Cleavage[J]. J Invest Dermatol, 2021, 141(1): 36-47.
|
| [39] |
Russo V, Klein T, Lim DJ, et al. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction[J]. Sci Rep, 2018, 8(1): 9690.
|
| [40] |
Hu HH, Chen DQ, Wang YN, et al. New insights into TGF-beta/Smad signaling in tissue fibrosis[J]. Chem Biol Interact, 2018, 292: 76-83.
|
| [41] |
Boivin WA, Shackleford M, Vanden HA, et al. Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-beta1[J]. PLoS One, 2012, 7(3): e33163.
|
| [42] |
孙云晖，王一新，马雪梅，等. 大鼠肺纤维化模型中NLRP3、IL-18表达及意义的探讨[J]. 临床肺科杂志，2018, 23(5): 817-820.
|
| [43] |
Zhang LM, Zhang Y, Fei C, et al. Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition[J]. Biochem Biophys Res Commun, 2019, 508(2): 660-666.
|
| [44] |
Xiao H, Li H, Wang JJ, et al. IL-18 cleavage triggers cardiac inflammation and fibrosis upon beta-adrenergic insult[J]. Eur Heart J, 2018, 39(1): 60-69.
|
| [45] |
Fix C, Bingham K, Carver W. Effects of interleukin-18 on cardiac fibroblast function and gene expression[J]. Cytokine, 2011, 53(1): 19-28.
|
| [46] |
Platis A, Yu Q, Moore D, et al. The effect of daily administration of IL-18 on cardiac structure and function[J]. Perfusion, 2008, 23(4): 237-242.
|
| [47] |
Reese SP, Underwood CJ, Weiss JA. Effects of decorin proteoglycan on fibrillogenesis, ultrastructure, and mechanics of type I collagen gels[J]. Matrix Biol, 2013, 32(7/8): 414-423.
|
| [48] |
Danielson KG, Baribault H, Holmes DF, et al. Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility[J]. J Cell Biol, 1997, 136(3): 729-743.
|
| [49] |
Shen Y, Zeglinski MR, Turner CT, et al. Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing[J]. Exp Mol Med, 2018, 50(5): 1-11.
|