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中华损伤与修复杂志(电子版) ›› 2016, Vol. 11 ›› Issue (03) : 232 -235. doi: 10.3877/cma.j.issn.1673-9450.2016.03.016

所属专题: 文献

综述

胶原/羟基磷灰石复合材料的制备及用于骨缺损修复的研究现状
陈利1, 陈月2,(), 王宗良3, 王宇3, 章培标4   
  1. 1. 130021 长春,吉林大学药学院;130022 中国科学院长春应用化学研究所生态环境高分子材料重点实验室
    2. 130021 长春,吉林大学药学院
    3. 130022 中国科学院长春应用化学研究所生态环境高分子材料重点实验室;100039 北京,中国科学院大学
    4. 130022 中国科学院长春应用化学研究所生态环境高分子材料重点实验室
  • 收稿日期:2016-01-24 出版日期:2016-06-01
  • 通信作者: 陈月
  • 基金资助:
    国家自然科学基金项目(51403197,51203152)

Preparation of collagen/hydroxyapatite composites and its research in the repair for bone defect

Li Chen1, Yue Chen2,(), Zongliang Wang3, Yu Wang3, Peibiao Zhang4   

  1. 1. College of Pharmacy, Jilin University, Changchun 130021, China; Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
    2. College of Pharmacy, Jilin University, Changchun 130021, China
    3. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China; University of Chinese Academy of Sciences, Beijing 100039, China
    4. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
  • Received:2016-01-24 Published:2016-06-01
  • Corresponding author: Yue Chen
  • About author:
    Corresponding author: Chen Yue, Email:
引用本文:

陈利, 陈月, 王宗良, 王宇, 章培标. 胶原/羟基磷灰石复合材料的制备及用于骨缺损修复的研究现状[J]. 中华损伤与修复杂志(电子版), 2016, 11(03): 232-235.

Li Chen, Yue Chen, Zongliang Wang, Yu Wang, Peibiao Zhang. Preparation of collagen/hydroxyapatite composites and its research in the repair for bone defect[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2016, 11(03): 232-235.

通过模拟天然骨的结构,制备胶原/羟基磷灰石复合材料,与天然骨具有相似的组成、结构和性能,并具有良好的生物活性和生物降解性。本文就胶原/羟基磷灰石复合材料的制备方法、仿生形成机制、表征手段及骨缺损修复的应用等进行综述,并展望其未来发展方向。

Collagen/hydroxyapatite composites have been fabricated with similar composition, structure and properties with natural bone by simulating its structure. In this paper, the authors will review the preparation methods, biomimetic formation mechanism, characterization methods, applications in bone defect repair, as well as the prospect of collagen/hydroxyapatite composites.

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