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中华损伤与修复杂志(电子版) ›› 2021, Vol. 16 ›› Issue (03) : 245 -250. doi: 10.3877/cma.j.issn.1673-9450.2021.03.014

所属专题: 文献

论著

水动力清创系统用于深Ⅱ度烧伤创面治疗临床疗效的回顾性研究
王磊1, 蔡玉辉1, 胡克苏1, 朱兴华1, 张逸1,()   
  1. 1. 226001 南通大学附属医院烧伤整形科
  • 收稿日期:2021-03-01 出版日期:2021-06-01
  • 通信作者: 张逸
  • 基金资助:
    江苏省科技厅产学研合作项目(BY2020208); 南通市科技局基金项目(HS2020006); 南通市科技局项目(MSZ20121); 南通市科技局项目(MSZ19147)

Retrospective study on the clinical effect of hydrosurgery system in the treatment of deep partial-thickness burn wound

Lei Wang1, Yuhui Cai1, Kesu Hu1, Xinghua Zhu1, Yi Zhang1,()   

  1. 1. Department of Burns and Plastic Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China
  • Received:2021-03-01 Published:2021-06-01
  • Corresponding author: Yi Zhang
引用本文:

王磊, 蔡玉辉, 胡克苏, 朱兴华, 张逸. 水动力清创系统用于深Ⅱ度烧伤创面治疗临床疗效的回顾性研究[J/OL]. 中华损伤与修复杂志(电子版), 2021, 16(03): 245-250.

Lei Wang, Yuhui Cai, Kesu Hu, Xinghua Zhu, Yi Zhang. Retrospective study on the clinical effect of hydrosurgery system in the treatment of deep partial-thickness burn wound[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(03): 245-250.

目的

分析水动力清创系统用于深Ⅱ度烧伤创面清创的临床疗效,为深Ⅱ度烧伤创面的治疗提供新的思路和方法。

方法

选取南通大学附属医院烧伤整形科2018年1月至2019年12月收治的符合入院标准的深Ⅱ度烧伤患者40例,烧伤面积为2%~29%总体表面积(TBSA),位于躯干、四肢的非关节功能部位的创面[(100±10) cm2]区域为试验窗口区。按照随机数字表法将入组患者分为观察组与对照组,每组20例。所有患者在入院后均使用0.5%聚乙烯吡咯烷酮-碘消毒液作创面消毒,无菌纱布敷料包扎。观察组试验窗口区采用VERSAJET Ⅱ水动力清创系统进行创面清创,对照组试验窗口区采用常规手术器械进行创面清创。2组患者试验窗口区清创后创面用脂质水胶敷料覆盖,消毒纱布包扎,其余创面在试验窗口区清创结束后根据研究者判断及患者意愿选择相应清创方法。清创术后根据患者情况给予抗感染、营养补充等对症治疗,定期行创面换药直至创面愈合。观察2组患者创面坏死组织清除率,创面愈合时间,清创术后第7、14、21天创面感染情况及肝功能、肾功能、凝血象、血常规化验指标数值波动情况。对数据行t检验。

结果

观察组患者创面坏死组织清除率为(93.5±2.4)%,相比对照组[(91.3±3.9)%]明显提高,差异有统计学意义(t=-3.371,P<0.05);观察组患者创面愈合时间为(15.8±3.0) d,相比对照组[(18.5±3.6) d]明显缩短,差异有统计学意义(t=2.960,P<0.05);观察组患者清创术后第7天创面感染评分为(2.75±0.44)分,相比对照组[(2.55±0.51)分],差异无统计学意义(t=-1.165,P>0.05);观察组患者清创术后第14、21天创面感染评分为(1.60±0.26)、(0.80±0.19)分,相比对照组[(2.35±0.67)、(1.25±0.97)分]明显降低,差异均有统计学意义(t=4.156、3.244,P<0.05);2组患者手术清创前、后的肝功能、肾功能、凝血象、血常规等化验指标均未见明显波动。

结论

应用VERSAJET Ⅱ水动力清创系统进行深Ⅱ度烧伤创面清创,能更好地清除坏死组织,控制创面感染,缩短创面愈合时间且安全有效。

Objective

To analyze the clinical efficacy of hydrosurgery system in the treatment of deep partial-thickness burn wound, and to provide new ideas and methods for the treatment of deep partial-thickness burn wound.

Methods

From January 2018 to December 2019, 40 patients with deep partial-thickness burns who met the selection criteria were selected from the Department of Burns and Plastics, Affiliated Hospital of Nantong University. The burns area was 2%-29% of the total body surface area (TBSA). The wound area located in the non joint functional parts of the trunk and limbs (100±10) cm2 was the experimental window area. The patients were divided into two groups according to random number table method, 20 cases in each group. All patients were treated with 0.5% polyvinylpyrrolidone iodine disinfectant for wound disinfection after admission, then bandaged with sterile gauze dressing. Versajet Ⅱ hydrodynamic debridement system was used for wound debridement in the test window area of the observation group. Conventional surgical instruments were used for wound debridement in the test window area of the control group. After debridement, the wounds of the two groups were covered with lipid water gel dressing in the test window area, bandaged with sterile gauze. After debridement in the window area of the test area, the corresponding debridement methods were selected according to the judgment of the researchers and the wishes of the patients. After debridement, symptomatic treatment such as anti-infection and nutritional supplement was given to the patients according to their conditions. Wound dressing was changed regularly until wound healing. The rate of wound necrosis tissue clearance, infection after operation, wound healing time were observed, and the wound infection, liver function, renal function, coagulation blood image and blood routine test index at 7, 14, 21 days after debridement were observed in the two groups. Data was processed with t test.

Results

The wound necrotic tissue clearance rate of the observation group was (93.5±2.4)%, which was significantly higher than that of the control group [(91.3±3.9)%], the difference was statistically significant (t=-3.371, P< 0.05); the wound healing time of the observation group [(15.8±3.0) d] was significantly shorter than that of the control group [(18.5±3.6) d], the difference was statistically significant (t=2.960, P< 0.05); the wound infection score of the observation group was (2.75±0.44) scores 7 days after febridement, compared with that of the control group [(2.55±0.51) scores], the difference was not statistically significant (t=-1.165, P> 0.05); the wound infection score of the observation group was (1.60±0.26), (0.80±0.19) scores at 14, 21 days after debridemen, which were significantly lower than those in the control group [(2.35±0.67), (1.25±0.97) scores], the difference were statistically significant (t=4.156, 3.244; P< 0.05); there was no significant fluctuation in the preoperative and postoperative liver function, renal function, coagulation, blood routine test indexes of the two groups.

Conclusions

Versajet Ⅱ hydrosurgery system debridement can better clear the necrotic tissues, control the infection of the wounds, shorten the healing time of the wounds and it is safe and effective in the treatment of deep partial-thickness burns.

表1 2组深Ⅱ度烧伤患者一般资料比较
表2 2组深Ⅱ度烧伤患者创面坏死组织清除率及创面愈合时间比较(±s)
表3 2组深Ⅱ度烧伤患者创面感染评分比较(分,±s)
图1 采用水动力清创系统对右前臂深Ⅱ度烧伤创面行清创治疗。A示术中消毒铺单后右前臂试验窗口区深Ⅱ度创面(17 cm×6 cm);B示水动力清创系统清创结束后创面无坏死组织残留,呈针尖状渗血;C示清创术后第7天创面换药,创面新鲜,无感染,分泌物少,未见坏死组织残留;D示清创术后第16天,创面完全愈合
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