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中华损伤与修复杂志(电子版) ›› 2021, Vol. 16 ›› Issue (03) : 260 -264. doi: 10.3877/cma.j.issn.1673-9450.2021.03.017

所属专题: 文献

综述

脂肪间充质干细胞外泌体促进创面修复的研究进展
沈括1, 张锦鑫2, 王洪涛1, 胡大海1,()   
  1. 1. 710032 西安,空军军医大学第一附属医院烧伤与皮肤外科,全军烧伤中心
    2. 710032 西安,空军军医大学第一附属医院烧伤与皮肤外科,急诊科
  • 收稿日期:2021-05-10 出版日期:2021-06-01
  • 通信作者: 胡大海
  • 基金资助:
    国家自然科学基金重点项目(81530064); 国家自然科学基金面上项目(81772071,81971835)

Research progress of exosomes derived from adipose derived mesenchymal stem cell in wound healing

Kuo Shen1, Jinxin Zhang2, Hongtao Wang1, Dahai Hu1,()   

  1. 1. Department of Burns and Cutaneous Surgery, Burn Center of PLA, Air Force Medical University, Xi′an 710032, China
    2. Department of Emergency, First Affiliated Hospital, Air Force Medical University, Xi′an 710032, China
  • Received:2021-05-10 Published:2021-06-01
  • Corresponding author: Dahai Hu
引用本文:

沈括, 张锦鑫, 王洪涛, 胡大海. 脂肪间充质干细胞外泌体促进创面修复的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2021, 16(03): 260-264.

Kuo Shen, Jinxin Zhang, Hongtao Wang, Dahai Hu. Research progress of exosomes derived from adipose derived mesenchymal stem cell in wound healing[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(03): 260-264.

脂肪间充质干细胞(ADSC)外泌体作为细胞间交流的重要手段,在创面修复与组织再生方面的作用受到越来越多的关注。本文通过阐述ADSC外泌体在创面愈合中对成纤维细胞(Fb)、内皮细胞、角质形成细胞(KC)和巨噬细胞调控作用的研究进展,以期为创面修复提供新的思路。

Exosomes from adipose derived mesenchymal stem cell (ADSC), a crucial means of intercellular communication, have been widely applied in wound healing and tissue regeneration in recent years. This article mainly describes the research progress of regulative effects of ADSC exosomes on fibroblasts, endothelial cells, keratinocytes, and macrophages in the process of wound healing, in order to provide novel insight to wound healing.

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