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中华损伤与修复杂志(电子版)

中华损伤与修复杂志(电子版) ›› 2021, Vol. 16 ›› Issue (06) : 520 -524. doi: 10.3877/cma.j.issn.1673-9450.2021.06.011

综述

浓缩生长因子及其在促进损伤组织修复中的应用进展
陈诺1, 李羽霖1, 阮琼芳1, 谢卫国1,†()   
  1. 1. 430060　武汉大学同仁医院暨武汉市第三医院烧伤研究所
  • 收稿日期:2021-10-12 出版日期:2021-12-01
  • 通信作者: 谢卫国
  • 基金资助:
    重大疾病防治科技行动计划(2018-ZX-01S-001); 国家自然科学基金面上项目(81772097); 王正国创伤医学发展基金会项目(SZYZ-TR-10); 湖北省卫生健康委面上项目(WJ2021M260)

Concentrated growth factor and its application progress in promoting the repair of injured tissue

Nuo Chen1, Yulin Li1, Qiongfang Ruan1, Weiguo Xie1,†()   

  1. 1. Institute of Burns, Tongren Hospital of Wuhan University & Wuhan Third Hospital, Wuhan 430060, China
  • Received:2021-10-12 Published:2021-12-01
  • Corresponding author: Weiguo Xie
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陈诺, 李羽霖, 阮琼芳, 谢卫国. 浓缩生长因子及其在促进损伤组织修复中的应用进展[J]. 中华损伤与修复杂志(电子版), 2021, 16(06): 520-524.

Nuo Chen, Yulin Li, Qiongfang Ruan, Weiguo Xie. Concentrated growth factor and its application progress in promoting the repair of injured tissue[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(06): 520-524.

浓缩生长因子(CGF)是血小板浓缩制品的一种特殊形式，通过特定的全血差速离心程序制备而获得。生长因子用于组织缺损的修复已有多年历史，而CGF因富含多种生长因子在组织损伤修复领域受到广泛关注。本文对CGF的发展历史、作用机制、在各类组织损伤修复中的应用、目前存在的不足及未来发展作一综述。

关键词: 伤口愈合, 创伤和损伤, 浓缩生长因子, 应用进展

Concentrated growth factor(CGF)is a special form of platelet concentrate products, which is obtained through a specific whole blood differential centrifugation procedure. Growth factors have been used in the repair of tissue defects for many years, and CGF has received extensive attention in tissue injury repair field because of its richness in a variety of growth factors. This article reviews the development history, mechanism, application in the repair of various tissue injuries, current deficiencies and future development of CGF.

Key words: Wound healing, Wounds and injuries, Concentrated growth factor, Application progress
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