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中华损伤与修复杂志(电子版) ›› 2022, Vol. 17 ›› Issue (02) : 159 -162. doi: 10.3877/cma.j.issn.1673-9450.2022.02.013

综述

外源性应用P物质促进糖尿病慢性创面愈合的研究进展
张苗苗1, 余小平2, 付倩倩3, 周军利2,()   
  1. 1. 730000 兰州,甘肃中医药大学第一临床医学院
    2. 730000 兰州,甘肃省人民医院烧伤科
    3. 750000 银川,宁夏医科大学临床医学院
  • 收稿日期:2022-01-12 出版日期:2022-04-01
  • 通信作者: 周军利
  • 基金资助:
    国家自然科学基金(81460294)

Research progress of exogenous application of substance P to promote the healing of chronic diabetic wounds

Miaomiao Zhang1, Xiaoping Yu2, Qianqian Fu3, Junli Zhou2,()   

  1. 1. First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou 730000, China
    2. Department of Burns, Gansu Provincial Hospital, Lanzhou 730000, China
    3. Clinical Medical School, Ningxia Medical University, Yinchuan 750000, China
  • Received:2022-01-12 Published:2022-04-01
  • Corresponding author: Junli Zhou
引用本文:

张苗苗, 余小平, 付倩倩, 周军利. 外源性应用P物质促进糖尿病慢性创面愈合的研究进展[J]. 中华损伤与修复杂志(电子版), 2022, 17(02): 159-162.

Miaomiao Zhang, Xiaoping Yu, Qianqian Fu, Junli Zhou. Research progress of exogenous application of substance P to promote the healing of chronic diabetic wounds[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(02): 159-162.

糖尿病是世界范围内流行且患病例数逐年增加的一种严重疾病,糖尿病足溃疡是糖尿病的主要并发症之一。P物质(Substance P, SP)是一种以在感觉神经系统中发挥作用而闻名的神经肽,是一种对伤口愈合和免疫活性都具有重要作用的神经肽。本文就SP促进糖尿病环境下的慢性创面愈合机制作一综述。

Diabetes is a serious disease that is prevalent worldwide and increasing year by year. Diabetic foot ulcer is one of the main complications of diabetes.Substance P (SP) is a neuropeptide which plays an important role in wound healing and immune activity and is famous for its role in sensory nervous system. This article reviews the mechanism of SP promoting chronic wound healing in diabetic environment.

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