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中华损伤与修复杂志(电子版) ›› 2020, Vol. 15 ›› Issue (06) : 502 -505. doi: 10.3877/cma.j.issn.1673-9450.2020.06.015

所属专题: 文献

综述

干细胞来源外泌体在烧伤创面修复中的研究进展
符雪1, 李俊亮1, 徐洋1, 曹胜军1, 王凌峰1,()   
  1. 1. 014010 包头,内蒙古医科大学第三附属医院实验中心,烧伤科
  • 收稿日期:2020-10-08 出版日期:2020-12-01
  • 通信作者: 王凌峰
  • 基金资助:
    国家自然科学基金项目(81360293)

Research of stem cell-derived exosome in burn wound repair

Xue Fu1, Junliang Li1, Yang Xu1, Shengjun Cao1, Lingfeng Wang1,()   

  1. 1. Experiment Center, Department of Burns, Third Affiliated Hospital of Inner Mongolia Medical University, Baotou 014010, China
  • Received:2020-10-08 Published:2020-12-01
  • Corresponding author: Lingfeng Wang
  • About author:
    Corresponding author: Wang Lingfeng, Email:
引用本文:

符雪, 李俊亮, 徐洋, 曹胜军, 王凌峰. 干细胞来源外泌体在烧伤创面修复中的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2020, 15(06): 502-505.

Xue Fu, Junliang Li, Yang Xu, Shengjun Cao, Lingfeng Wang. Research of stem cell-derived exosome in burn wound repair[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2020, 15(06): 502-505.

外泌体通过与目标细胞融合,调控目标细胞的增殖、迁移和凋亡。其来源丰富,易于获取和储存,移植后不易诱发免疫排斥反应,在烧伤创面修复领域存在良好的应用前景。本文通过阐述外泌体生物特征、干细胞来源外泌体修复烧伤创面的机制及在创面修复领域的研究进展,以期为烧伤创面修复提供新思路。

Exosomes are able to regulate proliferation, migration, and apoptosis of target cells by fusing with them. Exosomes are abundant in source, easy to be acquired and stored, and not easy to induce immune rejection after transplantation. Therefore, exosomes have a good application prospect in the field of burn wound repair. In this paper, the biological characteristics of exosomes, the mechanism of stem cell derived-exosomes repairing burn wounds and the research progress in the field of wound repair are described, in order to provide new ideas for burns wound repair.

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