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中华损伤与修复杂志(电子版) ›› 2022, Vol. 17 ›› Issue (02) : 147 -153. doi: 10.3877/cma.j.issn.1673-9450.2022.02.011

综述

血小板浓缩物在慢性创面治疗中应用的研究进展
丁泓帆1, 郑兴锋2,(), 夏照帆2   
  1. 1. 上海 200433,海军军医大学基础医学院
    2. 上海 200433,海军军医大学第一附属医院烧伤外科
  • 收稿日期:2022-01-20 出版日期:2022-04-01
  • 通信作者: 郑兴锋
  • 基金资助:
    上海市科委医学引导类项目(18411966900)

Advances in the application of platelet concentrate in the treatment of chronic wounds

Hongfan Ding1, Xingfeng Zheng2,(), Zhaofan Xia2   

  1. 1. Basic Medical College, Navy Medical University, Shanghai 200433, China
    2. Department of Burns Surgery, First Affiliated Hospital, Navy Medical University, Shanghai 200433, China
  • Received:2022-01-20 Published:2022-04-01
  • Corresponding author: Xingfeng Zheng
引用本文:

丁泓帆, 郑兴锋, 夏照帆. 血小板浓缩物在慢性创面治疗中应用的研究进展[J]. 中华损伤与修复杂志(电子版), 2022, 17(02): 147-153.

Hongfan Ding, Xingfeng Zheng, Zhaofan Xia. Advances in the application of platelet concentrate in the treatment of chronic wounds[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(02): 147-153.

随着再生医学和组织工程等学科的不断进步,血小板浓缩物(PC)被逐步应用于慢性创面的治疗领域。本文归纳了血小板浓缩物的3代产品——富血小板血浆(PRP),富血小板纤维蛋白(PRF)和浓缩生长因子(CGF)的发展过程和各自特点以及其在促进创面愈合中的机制,同时就3代血小板浓缩物各自在慢性创面的治疗应用研究进展以及其局限性等进行了回顾总结,并对血小板浓缩物在创面修复中的应用价值和发展瓶颈进行了展望。

With the development of regenerative medicine and tissue engineering, platelet concentrate (PC) has been gradually applied in the treatment of chronic wounds. The development process and characteristics of three generations of platelet concentrates—platelet rich plasma(PRP), platelet rich fibrin (PRF) and concentrated growth factor (CGF) and their mechanisms in promoting wound healing have been summarized in this article. This paper also reviews the research progress and limitations of three generations of platelet concentrate in the treatment of chronic wound, and look forward to the application value and development bottleneck of platelet concentrate in wound repair.

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