Regulation of intestinal stem cells and tissue damage and repair after radiation exposure

doi:10.3877/cma.j.issn.1673-9450.2023.04.016

Abstract

Abstract:

Intestinal tract is an important target organ of radiation injury. The degree of tissue damage and repair directly affects the prognosis of patients with radiation combined injury and other type of intestinal radiation injuries. So far, there is still a lack of effective clinical methods to treat radiation damage. The regulation of intestinal stem cells plays a central role in the development of radiation-induced intestinal injury. Study on intestinal stem cells identity, signal regulation, pathological process and drug screening, can provide references for the treatment of related diseases.

Key words: Intestinal stem cell, Signal transduction, Irradiation, Tissue damage and repair

Linfeng He, Yu Cao, Ning Zhang, Xinze Ran, Fengchao Wang. Regulation of intestinal stem cells and tissue damage and repair after radiation exposure[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2023, 18(04): 358-363.

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https://zhssyxfzz.cma-cmc.com.cn/EN/Y2023/V18/I04/358

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