Diabetic foot ulcer is the most common and serious complications of diabetes. Peripheral neuropathy, peripheral artery disease and trauma are the main factors leading to foot ulcers, and poor wound healing can lead to the occurrence of chronic wounds, often leading to amputation. Although multidisciplinary treatment has become a widespread consensus, timely and effective surgical intervention can control wound infection, promote wound healing and reduce the incidence of amputation. In order to standardize the surgical treatment of diabetic foot wounds, the expert group mainly discussed and reached a consensus from the aspects of local adjuvant therapy, interventional therapy, vascular reconstruction, debridement and surgical treatment, providing reference for medical staff in relevant clinical specialties.

The necrotizing fasciitis of diabetic foot, rapid onset and development, can rapidly progress to extensive necrosis of the skin, subcutaneous adipose tissue, superficial fascia and deep fascia, with a high risk of amputation and mortality. The pathophysiology of necrotizing fasciitis of diabetic foot is associated with peripheral neuropathy, peripheral arterial disease, infection and so on. However, the pathophysiology of necrotizing fasciitis of diabetic foot is complicated and remains unclear. The clinical treatment in necrotizing fasciitis of diabetic foot involves wound debridement, anti-infection and so on. However, most patients in early stages of necrotizing fasciitis of diabetic foot are easily misdiagnosed, to which should be paid great attention. The purpose of the present article is to review and discuss the pathophysiology, diagnose and treatment in necrotizing fasciitis of diabetic foot, in order to providing the theory basis for it.

Vibrio vulnificus, as an opportunistic pathogen, is common in people with chronic liver disease, diabetes and other basic diseases. The history of seafood exposure is a major feature of Vibrio vulnificus infection. Because of its rapid progress and high mortality, Vibrio vulnificus has increasingly attracted clinical attention. The purpose of this paper is to review the pathogenic mechanism of Vibrio vulnificus infection, and to provide new ideas for clinical diagnosis, treatment and prevention.

Burn medicine in China has developed for more than 60 years. In the times of poor conditions and many difficulties, the old generation of medical workers, with a strong sense of responsibility and enthusiasm for the burn cause, made extraordinary efforts, and achieved world-wide success with their hard-working hands and burning passion. The striking original results have contributed valuable wealth to burn medicine. Based on the published data, this paper briefly describes the achievements made in burn clinical treatment and basic research in my country before 2000, especially from the 1950s to the 1990s, briefly summarizes the narration according to the time axis of the occurrence of events. Its purpose is to inspire medical workers in the new era to seize opportunities, strive for strength, and make good use of modern good resources, earnestly study basic theories, attach importance to clinical practice, learn from foreign experience, and inspire us to carry forward the noble medical ethics, tenacious work and selfless dedication of our predecessors, and contribute to the national rejuvenation and the stronger burn cause in China.

The skin fibroblasts are the main repair cells involved in wound healing. In recent years, their heterogeneity and their communication with nearby cells have gradually attracted attention. The subgroups of dermal fibroblasts mainly include papillary fibroblasts and reticular fibroblasts, which play different roles in wound healing. The fibroblasts interact with nearby cells through autocrine and paracrine signal molecules to form the wound microenvironment, which affects wound healing. The fibroblasts in chronic wounds show a variety of dysfunctions. This article reviews the origin, phenotype, communication with nearby cells of fibroblasts and their dysfunction in chronic wounds.

Hand deep burns (HDB) is one of the main reasons for resulting in physical disabilities of patients with burns, especially serious burns. Effective treatment of HDB requires the integrated application of multidisciplinary ideas and technical approaches, including burns, plastic surgery, rehabilitation medicine and physical therapy. Early accurate treatment of HDB is the basis for the best recovery of hand function. The treatment goals include effective prevention of secondary injuries, early wound closure and early functional rehabilitation, etc.This article is based on the principles of evidence-based medicine, reviewing relevant literature and combining with the practice of Department of Burns and Plastic Surgery, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, to analyze and summarize the clinical and pathological characteristics of HDB, clinical evaluation and decompression treatment, early resection and skin (valve) transplantation, surgical treatment and early functional rehabilitation experience.

The original micro-skin grafting technology in China has been applied to repair the extremely large and deep burn wounds with severe lack of autologous skin sources and achieved remarkable results. In recent years, researchers at home and abroad have continuously improved and innovated the technology of microne skin transplantation based on the theory of microne skin transplantation, and expanded its application field. This paper mainly introduces the innovative preparation methods and equipment of microne skin tissue in recent years, and the related research progress of the innovative application of microne skin tissue in other clinical fields. With the standardization and simplification of preparation methods and processes, microne skin tissue transplantation will be applied to more and more clinical scenes, showing a good clinical effect and application prospects.

Diabetic foot is one of the long-term and serious complications of diabetes. It is characterized by complex etiology, great difficulty in treatment, rapid development of the disease, and has high disability and mortality. When patients with foot ulcers are not treated in time and effectively, local wound infection is easy to occur. Once myofascia space infection occurs and tension reduction and drainage is not timely, the infection will spread and spread rapidly, causing foot swelling or gangrene, and even systemic infection endangering life. Therefore, this article reviews the debridement drainage methods of the open debridement, vacuum sealing drainage and small incision counterpart drainage technology, elaborates the specific technical points, technical advantages and technical focus of the three debridement and drainage methods for preserving limbs in patients with diabetic foot with myofascial space infection, to provide a reference for diabetic foot multidisciplinary team to formulate a scientific and appropriate treatment plan, in order to promote the early recovery of diabetic foot ulcer patients and ensure the effectiveness of the overall treatment.

In recent years, although the basic research and clinical treatment of diabetic foot have made great progress, no breakthrough has been made. Limb salvage or amputation is always the perplexity of clinical thinking and the difficulty of clinical treatment decision of severe diabetic foot. Although limb salvage is still the mainstream view and treatment option, amputation does not mean treatment failure. This paper discusses the advantages and disadvantages of the two concepts, arguing that patients with passive amputation often have poor general condition and poor prognosis (death/wound healing of amputation), and proposes that targeted, predictive and proactive amputation should be selected for patients with severe diabetic foot according to the condition and limb function, in order to achieve rapid control of the disease, shorten the length of hospitalization and obtain a better prognosis outcome. At the same time, it is proposes that a multicenter comparative clinical study of the long-term efficacy of the two treatment options should be conducted as soon as possible.

Fibroblasts are one of the important effector cells in the wound healing process and are involved in several important aspects. Different subpopulations of fibroblasts exhibit strong heterogeneity depending on different aspects of their anatomical localization, cell surface markers, and functional phenotypes. This paper reviews the heterogeneous characteristics of fibroblasts and their role in wound healing and scar formation, with the aim of providing a new theoretical basis for wound repair therapy.

Wound is normal skin tissue damage caused by physical, chemical, pathogenic microorganisms or local blood circulation obstacle. Wound repair is an increasingly important global problem, and dressings play an important role in wound repair. Selecting appropriate dressings according to the specific conditions of the wound can prevent wound infection and improve the comfort of patients in the treatment process. However, there are various types and characteristics of dressings in clinical practice, so how to choose dressings is a difficult problem faced by clinicians. This paper reviews the characteristics and indications of various new wound dressings, aiming to provide reference for clinicians to select appropriate wound dressings.

Skin tears is one of the common skin injuries in elderly hospitalized patients, except for stress injuries. After skin damage, the damage degree is serious, which eventually leads to the increase of hospitalization costs and safety risks. At present, many foreign scholars have studied it, while only a few domestic scholars have conducted multi-center cross-sectional studies on it. Medical institutions have not paid enough attention to it and trained enough, nursing staff lack of cognition and related knowledge, and no systematic and standardized intervention measures have been formed for the prevention and nursing of skin tears. This consensus is based on the existing research at home and abroad, combined with the characteristics of elderly patients and the scope of diagnosis and treatment, respectively from the classification of skin tears, injury site, risk factors, causes, risk management, prevention and care and other aspects of the discussion to form a national expert consensus, to provide basis and guidance for elderly patients skin management and clinical nursing practice.