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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2023, Vol. 18 ›› Issue (05): 447-450. doi: 10.3877/cma.j.issn.1673-9450.2023.05.015

• Review • Previous Articles     Next Articles

Research progress of drug-induced pyoderma gangrenosum

Meiqi Lu, Jie Zhao, Fei Shan, Xinglei Wang, Duyin Jiang()   

  1. Department of Burns and Plastic Surgery, the Second Hospital of Shandong University, Jinan 250033, China
    Department of Emergency Medical Center, the Second Hospital of Shandong University, Jinan 250033, China
    Department of Burns and Plastic Surgery, the Second Hospital of Shandong University, Jinan 250033, China; Department of Emergency Medical Center, the Second Hospital of Shandong University, Jinan 250033, China
  • Received:2023-03-10 Online:2023-10-01 Published:2023-10-11
  • Contact: Duyin Jiang

Abstract:

Drug-induced pyoderma gangrenosum is an extremely rare neutrophilic dermatoses with unclear pathophysiology, difficult diagnosis and non-uniform treatment protocol. However, drug-induced pyoderma gangrenosum is a rare adverse drug reaction that often causes great suffering to patients. In this article, the pathogenesis, pathological examination, clinical manifestations, diagnosis and differential diagnosis, and treatment options of drug-induced pyoderma gangrenosum were reviewed, with the aim of providing a reference for the diagnosis and treatment of drug-induced pyoderma gangrenosum in clinical practice.

Key words: Pyoderma gangrenosum, Neutrophil extracellular traps, Mechanism, Treatment

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