To explore the effect of the repair of deep wounds with grafting of artificial dermis in combination with autologous miniature skin pillar dot seeding.

Fourteen patients with deep wounds admitted to Department of Burns and Wound Repair, Dongguan Houjie Hospital from May 2022 to June 2023 were enrolled in the study including 8 males and 6 females, with the mean age of 31-86 (47.7±10.7) years. Six patients got burns and frostbite, 3 patients got contusions and scratchs, 2 patients got varicose ulcers, 2 patients got diabetic foot, and 1 patient got car accident damage.All the wounds were covered by artificial dermis in combination with autologous miniature skin pillar dot seeding after debridement thoroughly. Wound healing and recurrence were observed.Vancouver scar scale (VSS) was used to score the pigmentation, height, vascurity and pliability of scars, and the total score was calculated. Adverse reactions during the treatment process were recorded.

All the grafted miniature skin pillar of fourteen patients were survived and fused, and the wounds were healed. The hospital stay was 6-51 (22.3±9.9)days, and the wound healing time was 12-42 (22.2±6.7) days. The total score of VSS was 1-4 (2.8±0.7) points. The color was similar to that of normal skin, the thickness was normal, the hyperemia was not obvious, and the texture was soft. There was no injury of donor site, scar contracture or dysfunction of the operating area after the operation.

Deep wounds can be satisfactorily repaired by grafting of artificial dermis in combination with autologous miniature skin pillar dot seeding with no injury of donor site or recurrence after the operation, which provides a new type of therapy for the management of deep wounds.