探讨自制便携式简易负压辅助闭合疗法对下肢慢性溃疡的治疗效果以及可行性。

选取徐州市中心医院烧伤整形科2016年1月至2017年1月收治的30例下肢慢性溃疡患者，采用随机数字表法将患者分为对照组和试验组，每组15例，对照组外用重组人表皮生长因子凝胶＋湿润烧伤膏包扎，根据创面渗出情况每1～2 d换药1次，待创面肉芽组织新鲜且无明显渗出后可3 d换药1次。试验组采用凡士林纱布、无菌纱布、输液皮管、注射器及手术贴膜，自制便携式简易负压辅助闭合装置进行治疗，每更换1次简易负压为1个疗程，前期每4～5 d更换1次简易负压，创面基底条件好转、肉芽组织生长良好后每5～7 d更换1次简易负压。观察2组患者创面换药次数及愈合时间。对数据行t检验。

试验组换药次数为(4.1±0.8)次，创面愈合时间为(16.5±2.5) d，对照组换药次数为(11.4±2.3)次，创面愈合时间为(22.9±4.5) d, 2组之间比较，差异均有统计学意义(t＝11.698、4.838，P值均小于0.05)。

自制便携式简易负压辅助闭合疗法是一种创新性的实用型设计，对下肢慢性溃疡的治疗效果显著，能减少换药次数，缩短创面愈合时间，操作简单，携带方便，在病房及门诊均值得进一步推广应用。

To explore the effect and feasibility of self-made portable simplified vacuum-assisted closure therapy for patients with chronic ulcer of lower extremity.

Thirty patients from the Department of Burns and Plastic Surgery, Xuzhou Central Hospital from January 2016 to January 2017 with chronic ulcer of lower extremity were divided into control group and experimental group according to the random number table method. The control group was treated with routine dressing change using recombinant human epidermal growth factor gel and moist exposed burn ointment every 1 to 2 days according to the exudation of the wound, and it was prolonged to 3 days when the granulation became fresh with no exudation. While the experimental group was treated with self-made portable simplified vacuum-assisted closure therapy, which was made by vaseline gauze, sterile gauze, infusion tube, syringe and surgical patch. It was defined as a course of treatment when changing the vacuum-assisted closure. It was changed every 4 to 5 days at first and was prolonged to 5 to 7days when the wound basal condition was improved and the granulation tissue grew well. The recovery of wound was observed with times of dressing change as well as days to complete healing. Data were processed with t test.

The dressing change times of experimental group and control group were respectively (4.1±0.8) times and (11.4±2.3) times, while the healing time of the two groups were respectively (16.5±2.5) days and (22.9±4.5) days. There were significant differences between the two groups (t=11.698, 4.838; with P values below 0.05).

The self-made portable simplified vacuum-assisted closure therapy was a useful and effective method for patients with chronic ulcer of lower extremity, which can reduce the times of dressing change and shorten the wound healing time. The utility model has the advantages of simple operation and convenient carrying, and is worthy of further popularization and application in the ward as well as the outpatient department.