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中华损伤与修复杂志(电子版) ›› 2024, Vol. 19 ›› Issue (05) : 453 -456. doi: 10.3877/cma.j.issn.1673-9450.2024.05.014

综述

应用基质血管成分细胞治疗糖尿病足溃疡的研究进展
别瑶1, 曹志斌1, 辛静2, 王健楠1, 惠宗光1,()   
  1. 1. 261000 潍坊,山东第二医科大学附属医院内分泌代谢病科
    2. 261000 潍坊,山东第二医科大学附属医院浮烟山院区内科
  • 收稿日期:2024-02-21 出版日期:2024-10-01
  • 通信作者: 惠宗光
  • 基金资助:
    山东省中医药科技项目(M-2022238); 潍坊医学院附属医院博士启动基金(2020BSQD01)

Research progress of stromal vascular fraction cells in the treatment of diabetic foot ulcer

Yao Bie1, Zhibin Cao1, Jing Xin2, Jiannan Wang1, Zongguang Hui1,()   

  1. 1. Department of Endocrine and Metabolic Diseases, Affiliated Hospital of Shandong Second Medical University, Weifang 261000, China
    2. Fuyanshan Branch, Department of Medicine Affiliated Hospital of Shandong Second Medical University, Weifang 261000, China
  • Received:2024-02-21 Published:2024-10-01
  • Corresponding author: Zongguang Hui
引用本文:

别瑶, 曹志斌, 辛静, 王健楠, 惠宗光. 应用基质血管成分细胞治疗糖尿病足溃疡的研究进展[J]. 中华损伤与修复杂志(电子版), 2024, 19(05): 453-456.

Yao Bie, Zhibin Cao, Jing Xin, Jiannan Wang, Zongguang Hui. Research progress of stromal vascular fraction cells in the treatment of diabetic foot ulcer[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2024, 19(05): 453-456.

基质血管成分细胞是一种脂肪组织来源的异质细胞群,具有增殖分化潜能和旁分泌作用,可促进移植部位血管再生,从而实现血液循环重建,改善血供,促进糖尿病足溃疡愈合。因此,基质血管成分细胞可以应用于糖尿病足溃疡的治疗,且具有独特优势和治疗价值。本文对基质血管成分细胞促进糖尿病足溃疡愈合的机制进行综述,希望为临床研究与治疗提供参考。

Stromal vascular fraction cells are heterogeneous cells derived from adipose tissue that have the potential to proliferate, differentiate and paracrine, can promote angiogenesis at the transplantation site, and achieve revascularization and improved blood supply, promote the healing of diabetic foot ulcer. Therefore, stromal vascular fraction cells can be used in the treatment of diabetic foot ulcer, and have unique advantages and therapeutic value. This article reviews the mechanism of stromal vascular fraction cells in promoting the healing of diabetic foot ulcers, and hope for providing references for clinical research and treatment.

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