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中华损伤与修复杂志(电子版) ›› 2020, Vol. 15 ›› Issue (05) : 392 -396. doi: 10.3877/cma.j.issn.1673-9450.2020.05.012

所属专题: 文献

综述

糖尿病足坏死性筋膜炎病理生理机制及诊治
杨少玲1,(), 韩瑞2, 胡丽叶1   
  1. 1. 050082 石家庄,中国人民解放军联勤保障部队第980(白求恩国际和平)医院内分泌科
    2. 050000 石家庄,河北医科大学第一医院神经内科
  • 收稿日期:2020-07-15 出版日期:2020-10-01
  • 通信作者: 杨少玲
  • 基金资助:
    河北省卫生健康委员会指导性课题(20191191)

The pathophysiology and treatment in necrotizing fasciitis of diabetic foot

Shaoling Yang1,(), Rui Han2, Liye Hu1   

  1. 1. Department of Endocrinology, The 980th (Bethune International Peace) Hospital of the Joint Logistic Support Force of PLA, Shijiazhuang 050082, China
    2. Department of Neurology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Received:2020-07-15 Published:2020-10-01
  • Corresponding author: Shaoling Yang
  • About author:
    Corresponding author: Yang Shaoling, Email:
引用本文:

杨少玲, 韩瑞, 胡丽叶. 糖尿病足坏死性筋膜炎病理生理机制及诊治[J/OL]. 中华损伤与修复杂志(电子版), 2020, 15(05): 392-396.

Shaoling Yang, Rui Han, Liye Hu. The pathophysiology and treatment in necrotizing fasciitis of diabetic foot[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2020, 15(05): 392-396.

糖尿病足坏死性筋膜炎起病急、发展快,可迅速进展为皮肤、皮下脂肪组织、浅筋膜及深筋膜的广泛坏死,其截肢(趾)风险高,病死率高。糖尿病足坏死性筋膜炎病理生理机制包括糖尿病周围神经病变、糖尿病周围血管病变、感染等,但具体机制复杂,尚未完全明确,其治疗包括局部清创、抗感染等,但多数糖尿病足坏死性筋膜炎早期易误诊和漏诊,应引起高度重视。本文就糖尿病足坏死性筋膜炎病理生理机制、诊断及治疗进行综述,为提高对糖尿病足坏死性筋膜炎的认识和治疗提供理论和临床依据。

The necrotizing fasciitis of diabetic foot, rapid onset and development, can rapidly progress to extensive necrosis of the skin, subcutaneous adipose tissue, superficial fascia and deep fascia, with a high risk of amputation and mortality. The pathophysiology of necrotizing fasciitis of diabetic foot is associated with peripheral neuropathy, peripheral arterial disease, infection and so on. However, the pathophysiology of necrotizing fasciitis of diabetic foot is complicated and remains unclear. The clinical treatment in necrotizing fasciitis of diabetic foot involves wound debridement, anti-infection and so on. However, most patients in early stages of necrotizing fasciitis of diabetic foot are easily misdiagnosed, to which should be paid great attention. The purpose of the present article is to review and discuss the pathophysiology, diagnose and treatment in necrotizing fasciitis of diabetic foot, in order to providing the theory basis for it.

表1 LRINEC评分
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