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中华损伤与修复杂志(电子版) ›› 2025, Vol. 20 ›› Issue (03) : 260 -264. doi: 10.3877/cma.j.issn.1673-9450.2025.03.012

综述

创面微环境温度对慢性创面愈合影响的研究进展
杨纯旭1, 张玥2,(), 匡英杰1, 刘明2   
  1. 1. 250014 济南,山东中医药大学第一临床医学院
    2. 250014 济南,山东中医药大学附属医院周围血管病科
  • 收稿日期:2025-02-07 出版日期:2025-06-01
  • 通信作者: 张玥
  • 基金资助:
    山东省自然科学基金面上项目(ZR2022MH268)

A review of the effect of wound microenvironment temperature on chronic wound healing

Chunxu Yang1, Yue Zhang2,(), Yingjie Kuang1, Ming Liu2   

  1. 1. 1st Clinical Medical College of Shandong University of Traditional Chinese Medicine,Ji'nan 250014,China
    2. Department of Peripheral Vascular Diseases,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan 250014,China
  • Received:2025-02-07 Published:2025-06-01
  • Corresponding author: Yue Zhang
引用本文:

杨纯旭, 张玥, 匡英杰, 刘明. 创面微环境温度对慢性创面愈合影响的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2025, 20(03): 260-264.

Chunxu Yang, Yue Zhang, Yingjie Kuang, Ming Liu. A review of the effect of wound microenvironment temperature on chronic wound healing[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2025, 20(03): 260-264.

慢性创面的微环境存在多种异常情况,其中温度异常是影响创面愈合的重要因素。慢性创面由于血运和供氧受损,通常呈现低温状态,但在感染、炎症反应等病理状态下可能出现局部温度升高的现象。系统研究各类慢性创面的温度特征,对实现慢性创面的早期预警、评估及预后预测具有重要临床价值。通过研究温度对创面愈合的影响机制,探索温度调节策略,可为不同病理阶段的慢性创面提供个体化治疗依据,提供促进组织修复的新思路。

The microenvironment of chronic wounds exhibits multiple abnormalities, among which temperature dysregulation is a critical factor impeding wound healing.Chronic wounds typically manifest hypothermic conditions due to impaired blood supply and oxygenation, whereas pathological conditions such as infection and inflammatory responses may induce localized hyperthermia.Systematic investigation of thermal characteristics across various chronic wound types holds significant clinical value for early warning,precise assessment, and prognostic prediction.Elucidation of temperature-mediated influence mechanisms in wound repair and development of targeted temperature modulation strategies could provide the foundation for individualized therapeutic approaches tailored to distinct pathological stages of chronic wounds, ultimately providing novel strategies to enhance tissue regeneration.

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