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中华损伤与修复杂志(电子版) ›› 2026, Vol. 21 ›› Issue (04) : 309 -314. doi: 10.3877/cma.j.issn.1673-9450.2026.04.012

综述

负压伤口疗法联合生物活性敷料在糖尿病足溃疡中的应用研究进展
冯颖, 祝红娟(), 王倩, 高猛猛, 郭佳宁, 马妍   
  1. 100048 北京,解放军总医院第四医学中心烧伤整形医学部
  • 收稿日期:2026-03-13 出版日期:2026-08-01
  • 通信作者: 祝红娟

Research progress on the application of negative pressure wound therapy combined with bioactive dressings in diabetic foot ulcers

Ying Feng, Hongjuan Zhu(), Qian Wang, Mengmeng Gao, Jianing Guo, Yan Ma   

  1. Department of Burns and Plastic Surgery,the Fourth Medical Center of Chinese PLA General Hospital,Beijing 100048,China
  • Received:2026-03-13 Published:2026-08-01
  • Corresponding author: Hongjuan Zhu
引用本文:

冯颖, 祝红娟, 王倩, 高猛猛, 郭佳宁, 马妍. 负压伤口疗法联合生物活性敷料在糖尿病足溃疡中的应用研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(04): 309-314.

Ying Feng, Hongjuan Zhu, Qian Wang, Mengmeng Gao, Jianing Guo, Yan Ma. Research progress on the application of negative pressure wound therapy combined with bioactive dressings in diabetic foot ulcers[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2026, 21(04): 309-314.

糖尿病足溃疡(DFU)是糖尿病患者致残率最高的慢性并发症之一,临床治疗与护理难度显著,传统换药模式难以满足复杂创面的修复需求。负压伤口疗法(NPWT)联合生物活性敷料作为一种新型协同护理模式,通过物理力学干预与生物生化调节的双重作用,可有效改善创面微环境、促进组织再生,已成为DFU临床护理的核心手段。该文从临床护理视角出发,系统梳理该联合模式的临床应用基础、规范化护理操作流程、并发症预防与舒适护理措施,分析临床护理管理中的难点并提出针对性解决策略,同时展望其智能化护理发展趋势,旨在为临床护理人员提供标准化、精细化的实践参考,以提升DFU护理质量,降低患者截肢风险。

Diabetic foot ulcer (DFU) is one of the chronic complications with the highest disability rate among diabetic patients. Clinical treatment and nursing care are notably challenging,and traditional dressing change regimens are often inadequate for meeting the repair requirements of complex wounds. As a novel collaborative nursing model,negative pressure wound therapy (NPWT) combined with bioactive dressings can effectively improve the wound microenvironment and promote tissue regeneration through the dual effects of physical-mechanical intervention and bio-biochemical regulation,and has become a core approach in the clinical nursing of DFU. From the perspective of clinical nursing,this article systematically reviews the clinical application basis,standardized nursing operation procedures,complication prevention,and comfort care measures of this combined model,analyzes the difficulties in clinical nursing management and proposes targeted solutions,and also looks into its development trend towards intelligent nursing. This review aims to provide standardized and refined practical references for clinical nursing staff,so as to enhance the quality of DFU nursing and reduce the risk of amputation in patients.

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