Platelet rich plasma in the treatment of deep sternal wound infection: case report and literature review

doi:10.3877/cma.j.issn.1673-9450.2017.01.008

Abstract

Abstract:

Objective

To investigate the effect of platelet rich plasma in the treatment of sternal wound infection after sternotomy.

Methods

One case of deep sternal wound infection was reported which had been successfully treated with platelet rich plasma and related literatures with "sternal wound infection, sternal infection, mediastinitis, mediastinal infection, sternotomy, thoracic surgery and platelet rich plasma" were reviewed as searching terms in CNKI, Wanfang Data and PubMed.

Results

A 60 year-old female patient was admitted because of sternal wound remaining nonunion for 3 weeks after median sternotomy and was diagnosised as deep sternal wound infection. The wound was treated with platelet rich plasma and healed within 6 weeks accompanied by totally sternal closure. Five literatures with respect to platelet rich plasma in treatment for sternal wound infection were retrieved and prompts platelet rich plasma maybe an effective method for sternal wound infection.

Conclusions

Platelet rich plasma is an alternative treatment for sternal wound infection and it is essential to make further study and investigation.

Key words: Platelet rich plasma, Sternal wound infection, Sternotomy, Sternal osteomyelitis

Wanli Chu, Daifeng Hao, Jingfeng Zhao, Guang Feng, Tao Li, Haijun Zhang, Shanyou Li, Xinjian Zhang, Zequn Chen, Fan Zhao. Platelet rich plasma in the treatment of deep sternal wound infection: case report and literature review[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2017, 12(01): 46-51.

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Figures/Tables 2

References 30

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研究者	发表年份	研究类别	研究例数(PRP组/对照组)
孙斌等^[5]	2015	Meta分析	5613(2020/3593)
Serraino等^[6]	2015	历史对照研究	1093(422/671)
Hamman等^[4]	2014	历史对照研究	1866(548/1318)
D?rge等^[7]	2013	随机对照研究	196(97/99)
Lusini等^[8]	2012	个案报道	1

研究者	发表年份	研究类别	研究例数(PRP组/对照组)
孙斌等^[5]	2015	Meta分析	5613(2020/3593)
Serraino等^[6]	2015	历史对照研究	1093(422/671)
Hamman等^[4]	2014	历史对照研究	1866(548/1318)
D?rge等^[7]	2013	随机对照研究	196(97/99)
Lusini等^[8]	2012	个案报道	1

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