Progress of research on animal model of biliary calculi

doi:10.3877/cma.j.issn.1673-9450.2017.06.014

Abstract

Abstract:

Biliary calculi is a common disease, the incidence of it in China increased year by year, but the mechanism is still unknown. The selection and establishment of the ideal animal model is of great significance for studying the formation mechanism of biliary calculi. There are different ways to make animal models of biliary calculi according to the current formation mechanism of cholecystolithiasis. An efficient, fast and stable animal model of biliary calculi has been established to provide a reliable basis for clinical study of causes, mechanisms, prevention and the treatment of biliary calculi. This article summarizes a variety of methods to establish an animal model of biliary calculi and briefly reviews the pros and cons of establishing the animal model of biliary calculi.

Key words: Cholelithiasis, Models, animal, Lithogenic procedure

Xiaoyue Han, Rongquan Xue, Yijun Xia, Yi Sun, Longfu Xi, Jidong Bai. Progress of research on animal model of biliary calculi[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2017, 12(06): 470-472.

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https://zhssyxfzz.cma-cmc.com.cn/EN/Y2017/V12/I06/470

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