Advance research on scar-free healing of skin wounds

doi:10.3877/cma.j.issn.1673-9450.2020.04.018

Abstract

Abstract:

The skin acts as a defensive organ of the surface layer, and most animals have their wounds healed in the form of scar repair. In contrast, some species have the unique ability to regenerate skin without forming scar tissue, and even some mammals that are capable of regenerating skin attachments. The main mechanisms are related to cytokines, immune response and extracellular matrix (ECM) remodeling. This paper reviews the latest research progress of species with the ability to regenerate scar-free wound healing and reviews the characteristics of scar-free wound healing.

Key words: Cicatrix, Skin, Extracellular matrix, Immunity, Scar-free healing

Zhixun Zhang, Haihang Li, Shihui Zhu. Advance research on scar-free healing of skin wounds[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2020, 15(04): 322-325.

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