To retrospectively investigate the clinical diagnosis and treatment information of diabetic foot patients in the Wound Repair Center, Department of Burn and Plastic Surgery, Fourth Medical Center of PLA General Hospital, and analyze their clinical characteristics, to provide some reference for clinical treatment of diabetic foot patients.

The data of patients with diabetic foot admitted from January 1, 2014 to December 31, 2018 were retrospectively analyzed. The basic data, course of disease, wound information, treatment methods and outcomes were collected. To describe the epidemiological characteristics and to compare the effects of gender, course of disease, treatment methods on bacterial infection and therapeutic effect.

A total of 505 patients, including 321 males and 184 females, were enroll in the study. (1) The average age of the patients was (64.1 ± 12.9) years, and the patients aged 61-70 years were the largest (157 cases, 31.1%). The age of female patients was higher than that of male patients (F=22.532, P<0.001). (2)Five hundred and five patients were complicated with chronic complications. There were 381 cases with lower extremity atherosclerosis(75.45%), 318 cases with hypertension(62.97%), 168 cases with coronary atherosclerotic heart disease(33.27%) and 150 cases with old cerebral infarction(29.70%). (3) There were 119 cases with acute wounds and 386 cases with chronic wounds. (4) The most common sites of ulcer were toe (48.9%), pelma (16.2%), dorsum of foot (14.7%), ankle (11.1%) and heel (9.1%). (5)One hundred and sixty cases of diabetic foot ulcers were examined by microbiological examination, in which 135 (84.38%) were positive. Most of the acute wounds were infected by Gram-positive bacteria, and most of the chronic wounds were infected by Gram-negative bacteria(χ²=7.860, P<0.05). (6) Three hundred and one patients were treated with surgery, and 67 patients were treated with simple negative pressure therapy, 137 patients were treated with simple dressing change. One hundred and sixty-five patients (32.67%) were cured, 268 patients (53.07%) were improved, 71 patients (14.06%) were not healed, and 1 patient (0.198%) died. The cure rate of surgical treatment was significantly higher than that of simple negative pressure and dressing change(χ²=135.614, P<0.001).

The patiens are mainly middle-aged and elderly people which aged 51-70 years, which mostly are male patients. The age of female patients is higher than that of male patients. Most patients are complicated with chronic basic diseases, and attention should be paid to the treatment of basic diseases. The common sites of wound were toe, pelma, dorsum, ankle and heel. The bacterial infection rate is high which promotes the anti-infection treatment should be timely and reasonable. Compared with simple negative pressure and simple dressing change, the cure rate of surgical treatment is higher.