Research progress of chronic wounds with autoimmune diseases

doi:10.3877/cma.j.issn.1673-9450.2022.05.012

Abstract

Abstract:

Autoimmune disease is a kind of disease caused by the imbalance of immune tolerance caused by self-produced antibodies, which causes a series of chronic inflammatory reactions and tissue damage. If skin ulcer is complicated, the wound healing may be delayed or even unable to heal due to factors such as autoimmune factors and therapeutic drugs. Therefore, the treatment of such wounds is difficult, which often requires the joint diagnosis and treatment of multidisciplinary physicians. This article systematically reviews the pathogenesis, clinical characteristics, diagnosis and treatment of chronic refractory wounds with autoimmune diseases, in order to provide new insights for the diagnosis and treatment of autoimmune disease related skin ulcers.

Key words: Autoimmune disease, Skin ucler, Chronic wounds, Wound healing

Miaomiao Zhang, Qianqian Fu, Yamei Zhao, Xiaoping Yu, Junli Zhou. Research progress of chronic wounds with autoimmune diseases[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(05): 445-449.

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References 61

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疾病类型	病因	疾病名称
基因性疾病	先天性胶原合成错误	埃勒斯-当洛综合征
		马凡综合征
		成骨不全
		大疱性表皮松解
系统性疾病	代谢性疾病	糖尿病
		慢性肾功能衰竭
	营养性疾病	营养不良
		肥胖
		维生素缺乏症
	心血管疾病	慢性阻塞性肺疾病
		充血性心力衰竭
	自身免疫性疾病	血管炎
		类风湿关节炎
		系统性红斑狼疮
		坏疽性脓皮病
		硬皮病
		抗磷脂综合征
		抗中性粒细胞胞浆抗体相关血管炎
不良习惯	毒素	吸烟
		酗酒

疾病类型	病因	疾病名称
基因性疾病	先天性胶原合成错误	埃勒斯-当洛综合征
		马凡综合征
		成骨不全
		大疱性表皮松解
系统性疾病	代谢性疾病	糖尿病
		慢性肾功能衰竭
	营养性疾病	营养不良
		肥胖
		维生素缺乏症
	心血管疾病	慢性阻塞性肺疾病
		充血性心力衰竭
	自身免疫性疾病	血管炎
		类风湿关节炎
		系统性红斑狼疮
		坏疽性脓皮病
		硬皮病
		抗磷脂综合征
		抗中性粒细胞胞浆抗体相关血管炎
不良习惯	毒素	吸烟
		酗酒

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