Comparison of the anti-blocking performance between the new silicone rubber negative pressure drainage instillation system and the polyurethane negative pressure drainage system in vitro

doi:10.3877/cma.j.issn.1673-9450.2023.02.005

Abstract

Abstract:

Objective

To compare the anti-blocking performance between the new silicone rubber negative pressure drainage instillation system and traditional polyurethane negative pressure drainage system in vitro.

Methods

An in vitro anti-blocking experiment was designed. Established an wound vacuum sealing drainage model in vitro and simulated the wound surface with PVC plates. Liquid 1 (0.9% saline), liquid 2 (raw egg white mixed evenly), liquid 3 (20 g egg white mixed in 200 ml of 100 ℃ water) and liquid 4 (liquid 2 and liquid 3 mixed in 1∶1) were used to simulate different exudates and necrotic tissues of the wound, and the blockage of the two groups of negative pressure materials after being irrigated by four kinds of liquids under negative pressure of -50 mmHg to -300 mmHg was detected.

Results

The viscosities of liquid 1 to liquid 4 were (1.16±0.01) mPa.S, (4.27±0.01) mPa.S, (1.26±0.02) mPa.S, (3.26 ± 0.01) mPa.S. After the two negative pressure materials were irrigated with four kinds of liquids, they were both blocked, and the negative pressure was significantly reduced (P<0.05). In the liquid 1 group, under the conditions of -50 mmHg to -175 mmHg, there was no statistically significant difference in the blocking degree of the two kinds of negative pressure materials (P>0.05), but under the conditions of -200 mmHg to -300 mmHg, the blocking degree of the polyurethane negative pressure material was more serious than that of the anti-blocking negative pressure drainage tube with instillation (P<0.05). In the liquid 2-4 groups, the traditional polyurethane negative pressure material was significantly higher than the anti-blocking negative pressure drainage tube with instillation (P<0.05).

Conluusion

The new silicone rubber negative pressure drainage instillation system invented and designed by our group has good anti-blocking effect and can be applied to wounds with thick exudate and nonviable tissue.

Key words: Negative pressure wound therapy, Polyurethane, Catheter obstruction, Anti-blocking negative pressure drainage tube with instillation

Yanrong Zhai, Yaping Zhu, Xiuzhen Zhang, Xiaojuan Zhong, Xiangyue Lu, Yufan Zhang, Shuliang Lu. Comparison of the anti-blocking performance between the new silicone rubber negative pressure drainage instillation system and the polyurethane negative pressure drainage system in vitro[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2023, 18(02): 116-122.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhssyxfzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1673-9450.2023.02.005

https://zhssyxfzz.cma-cmc.com.cn/EN/Y2023/V18/I02/116

Figures/Tables 9

References 20

[1]	周琴，李双双，王青，等. 集束化护理干预对烧伤科住院患者负压封闭引流治疗中引流不畅的影响[J]. 中华烧伤杂志，2019，35(2)：148-152.
[2]	Norman G, Goh EL, Dumville JC, et al. Negative pressure wound therapy for surgical wounds healing by primary closure[J]. Cochrane Database Syst Rev, 2020，6(6)：CD009261.
[3]	Almeida IR, Coltro PS, Gonçalves H, et al. The role of negative pressure wound therapy (NPWT) on the treatment of pyoderma gangrenosum: a systematic review and personal experience[J]. Wound Repair Regen, 2021，29(3)：486-494.
[4]	Kirsner RS, Zimnitsky D, Robinson M. A prospective, randomized, controlled clinical study on the effectiveness of a single-use negative pressure wound therapy system, compared to traditional negative pressure wound therapy in the treatment of diabetic ulcers of the lower extremities[J]. Wound Repair Regen, 2021，29(6)：908-911.
[5]	吴石兵. 负压创面治疗技术(NPWT)在治疗难治性压疮中的临床应用[D]．苏州大学，2020.
[6]	Huang Z, Wang P, Pan ZY, et al. Randomized controlled trial on application of negative pressure materials of polyvinyl alcohol and polyurethane in full-thickness burn wounds after escharotomy[J]. Zhonghua Shao Shang Za Zhi, 2020，36(9)：813-820.
[7]	王采凤，杨志英. 不同频率生理盐水冲洗在负压封闭引流创面护理中的应用效果[J]. 中华现代护理杂志，2019，25(25)：3276-3279.
[8]	Wu L, Wen B, Xu Z, et al. Research progress on negative pressure wound therapy with instillation in the treatment of orthopaedic wounds[J]. Int Wound J, 2022，19(6)：1449-1455.
[9]	吕国忠，杨敏烈. 规范应用负压伤口疗法提高创面修复水平[J]. 中华烧伤杂志，2020，36(7)：523-527.
[10]	海峡两岸医药卫生交流协会烧创伤暨组织修复专委会，CROSS-STRAITS MEDICINE EXCHANGE ASSOCIATION OF CHINA. 负压伤口疗法在糖尿病足创面治疗中的应用全国专家共识(2021版)[J]. 中华烧伤杂志，2021，37(6)：508-518.
[11]	Ji S, Liu X, Huang J, et al. Consensus on the application of negative pressure wound therapy of diabetic foot wounds[J]. Burns Trauma, 2021，9：tkab018.
[12]	Faust E, Opoku-agyeman JL, Behnam AB. Use of negative-pressure wound therapy with instillation and dwell time: an overview[J]. Plast Reconstr Surg, 2021，147(1S-1)：16S-26S.
[13]	Cole W. Early-stage management of complex lower extremity wounds using negative pressure wound therapy with instillation and a reticulated open cell foam with through holes[J]. Wounds, 2020，32(6)：159-163.
[14]	武卫莉，李佳. 硅橡胶的生物医学材料特性[J]. 中国组织工程研究与临床康复，2007，11(1)：145-147.
[15]	Arowojolu OA, Wirth GA. Sacral and ischial pressure ulcer management with negative-pressure wound therapy with instillation and dwell[J]. Plast Reconstr Surg, 2021，147(1S-1)：61S-67S.
[16]	吴磊，周济宏，汤雨佳，等. 负压治疗结合滴注冲洗在伤口护理中的应用进展[J]. 中华护理杂志，2019，54(6)：950-954.
[17]	Cozza V, Pascale MM, Pepe G, et al. Empirical measurement of pressure in negative pressure wound therapy for infected wounds: How long can it really stay under pressure？[J]. Wound Repair Regen, 2019，27(2)：190-195.
[18]	Gibson DJ. A Comparison of the biomechanical performance of 3 negative pressure wound therapy foams[J]. J Wound Ostomy Continence Nurs, 2022，49(1)：51-58.
[19]	Delgado A, Sammons A. In vitro pressure manifolding distribution evaluation of ABThera(™) active abdominal therapy system, V．A.C.(^®) abdominal dressing system, and Barker′s vacuum packing technique conducted under dynamic conditions[J]. SAGE Open Med, 2016，4：2050312115624988.
[20]	Lindstedt S, Malmsjö M, Hlebowicz J, et al. Comparative study of the microvascular blood flow in the intestinal wall, wound contraction and fluid evacuation during negative pressure wound therapy in laparostomy using the V．A.C. abdominal dressing and the ABThera open abdomen negative pressure therapy system[J]. Int Wound J, 2015，12(1)：83-88.

组别	样本数	中心负压源(mmHg)
组别	样本数	－50	－75	－100	－125	－150	－175	－200	－225	－250	－300
聚氨酯组	12	－50.56±0.42	－66.23±0.22	－92.39±0.41	－118.84±0.49	－145.62±0.85	－172.03±0.37	－198.73±0.52	－224.42±0.48	－250.58±0.52	－303.57±0.88
防堵组	12	－50.85±0.32	－66.41±0.25	－92.51±0.22	－119.10±0.21	－145.52±0.28	－171.80±0.50	－198.42±0.39	－224.12±0.37	－250.20±0.47	－303.00±0.88
t值		1.92	1.81	0.87	1.67	－0.39	－1.26	－1.69	－1.73	－1.89	－1.58
P值		0.068	0.084	0.392	0.115	0.705	0.219	0.105	0.098	0.072	0.129

组别	样本数	中心负压源(mmHg)
组别	样本数	－50	－75	－100	－125	－150	－175	－200	－225	－250	－300
聚氨酯组	12	－50.56±0.42	－66.23±0.22	－92.39±0.41	－118.84±0.49	－145.62±0.85	－172.03±0.37	－198.73±0.52	－224.42±0.48	－250.58±0.52	－303.57±0.88
防堵组	12	－50.85±0.32	－66.41±0.25	－92.51±0.22	－119.10±0.21	－145.52±0.28	－171.80±0.50	－198.42±0.39	－224.12±0.37	－250.20±0.47	－303.00±0.88
t值		1.92	1.81	0.87	1.67	－0.39	－1.26	－1.69	－1.73	－1.89	－1.58
P值		0.068	0.084	0.392	0.115	0.705	0.219	0.105	0.098	0.072	0.129

Please choose a citation manager

Content to export