To investigate the effect of artificial dermis combined with vacuum sealing drainage with instillation in tendon or bone exposure wounds repair.

From January 2018 to January 2020, 39 cases of tendon or bone exposed wounds were treated in Department of Burns, First Affiliated Hospital of Anhui Medical University, including 26 cases of acute wounds (10 cases of trauma, 11 cases of burn, 4 cases of thermal pressure injury and 1 case of insect bite) and 13 cases of chronic wounds (2 cases of diabetic foot skin ulcer, 7 cases of later stage of burn, and 4 cases of scar ulcer). After debridement under general anesthesia or nerve block, the exposed tendons or bones were covered with reinforced artificial dermis. After operation, vacuum sealing drainage was performed with different irrigation solutions until the tissues were ruddy and reached the requirements of second stage skin grafting. The use times of artificial dermis, interval time between artificial dermis implantation and secondary skin grafting after debridement and survival of skin grafting were observed and recorded.

Thirty-nine cases of acute and chronic wound with tendon or bone exposure were covered with artificial dermis after debridement. Vacuum sealing drainage with different liquid instillation could promote granulation tissue formation after operation. Split-thickness skin graft in second stage survived 100% without infection and other complications.

Artificial dermis combined with vacuum sealing drainage with instillation can effectively cover the exposed tendon or bone, which is one of the effective repair method for acute and chronic wounds with tendon or bone exposure.