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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2024, Vol. 19 ›› Issue (04): 351-355. doi: 10.3877/cma.j.issn.1673-9450.2024.04.014

• Review • Previous Articles    

Research status of ventilator-associated pneumonia in burn patients with inhalation injury

Shijie Li1, Chuan′an Shen2,()   

  1. 1. PLA Medical School, Beijing 100853, China; Department of Burns and Plastic Surgery, the 4th Medical Center of PLA General Hospital, Beijing 100048, China
    2. PLA Medical School, Beijing 100853, China
  • Received:2024-01-26 Online:2024-08-01 Published:2024-08-09
  • Contact: Chuan′an Shen

Abstract:

Pulmonary infection is the most common complication and one of the main causes of death in burn patients. Burn patients with severe inhalation injury often need endotracheal intubation, which establishes a channel for pathogenic microorganisms to enter the lower respiratory tract and severe burns can lead to systemic immunosuppression.Inhalation injury not only destroys the airway defense mechanism, but also leads to airway local immunosuppression, which create conditions for ventilator-associated pneumonia (VAP) in burn patients. This article summarizes the current research results of VAP, and reviews the susceptibility factors, treatment and prevention of VAP in burn patients with inhalation injury, in order to provide reference for the treatment of ventilator-associated pneumonia in burn patients.

Key words: Burns, Pneumonia, ventilator-associated, Inhalation injury

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