Advancement of study on the mechanisms and treatment of injured typeⅡ alveolar epithelial cell in burn-blast combined injury

doi:10.3877/cma.j.issn.1673-9450.2016.06.015

Abstract

Abstract:

Burn-blast combined injury is common traumatic injury in both wars and daily life. It′s more serious than burn or blast injury, the treatment of burn-blast combined injury is more difficult, and it’s mortality is higher. Clinical data has shown that lung is the main target organ in the burn-blast combined injury. The degree of lung injury is closely related to the prognosis of patients with burn-blast combined injury. So the treatment of lung injury is the key factor for the treatment of burn-blast combined injury. Pre-clinical research has shown that the alveolar type Ⅱ epithelial cell (AEC Ⅱ) plays an important role in the development of the occurrence of lung injury during burn-blast combined injury.In recent years, the mechanism and and treatment of injured AEC Ⅱ in burn-blast combined injury has become one of the hotspots in the field of surgery. In this review, the mechanisms and treatment of injured ACE Ⅱ in burn-blast combined injury are discussed.

Key words: Burn-blast combined injury, Pulmonary alveoli, Epithelial cells, Lung injury

Rui Liu, Shuming Wang. Advancement of study on the mechanisms and treatment of injured typeⅡ alveolar epithelial cell in burn-blast combined injury[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2016, 11(06): 465-468.

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