Research progress of platelet-rich plasma in rheumatic diseases

doi:10.3877/cma.j.issn.1673-9450.2019.02.013

Abstract

Abstract:

Platelet-rich plasma(PRP) is enriched by a range of grow factors, chemokines, cytokines, and other plasma proteins, which can suppress inflammation and promote tissue regeneration. The interest in the application of PRP in rheumatology has recently increased. This paper reviews the research progress of PRP in osteoarthritis, rheumatoid arthritis, sjogren′s syndrome, systemic sclerosis, connective tissue disease-associated intractable skin ulcers and so on. In the future, more scholars need to actively try the efficacy of PRP in other rheumatic diseases. At the same time, PRP combined with mesenchymal stem cells has a great application prospect in refractory rheumatic diseases.

Key words: Platelet-rich plasma, Rheumatic diseases, Tissues, Repair

Jiaoniu Duan, Jinfang Gao, Liyun Zhang. Research progress of platelet-rich plasma in rheumatic diseases[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2019, 14(02): 145-148.

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References 32

[1]	Andia I, Maffulli N. Platelet-rich plasma for managing pain and inflammation in osteoarthritis[J]. Nat Rev Rheumatol, 2013, 9 (12): 721-730.
[2]	Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma(P-PRP)to leucocyte- and platelet-rich fibrin (L-PRF)[J]. Trends Biotechnol, 2009, 27(3): 158-167.
[3]	Alves R, Grimalt R. A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification[J]. Skin Appendage Disord, 2018, 4(1): 18-24.
[4]	Sherwood J. Osteoarthritis year in review 2018: biology[J]. Osteoarthritis Cartilage, 2019, 27(3): 365-370.
[5]	van Buul GM, Koevoet WL, Kops N, et al. Platelet-rich plasma releasate inhibits inflammatory processes in osteoarthritic chondrocytes[J]. Am J Sports Med, 2011, 39(11): 2362-2370.
[6]	Sundman EA, Cole BJ, Karas V, et al. The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis[J]. Am J Sports Med, 2014, 42(1): 35-41.
[7]	Moussa M, Lajeunesse D, Hilal G, et al.Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage[J]. Exp Cell Res, 2017, 352(1): 146-156.
[8]	Kwon DR, Park GY, Lee SU. The effects of intra-articular platelet-rich plasma injection according to the severity of collagenase-induced knee osteoarthritis in a rabbit model[J]. Ann Rehabil Med, 2012, 36(4): 458-465.
[9]	Khatab S, van Buul GM, Kops N, et al. Intra-articular Injections of Platelet-Rich Plasma Releasate Reduce Pain and Synovial Inflammation in a Mouse Model of Osteoarthritis[J]. Am J Sports Med, 2018, 46(4): 977-986.
[10]	解光越，陈阳，张志勇，等. 富白细胞血小板血浆联合兔滑膜干细胞促进膝关节软骨损伤修复的研究[J]. 中华实验外科杂志，2017, 3(10): 1718-1720.
[11]	Yin WJ, Xu HT, Zhang CQ, et al. Advantages of Pure Platelet-Rich Plasma compared with Leukocyte- and Platelet-Rich Plasma in Treating Rabbit Knee Osteoarthritis[J]. Med Sci Monit, 2016, 22: 1280-1290.
[12]	Yin W, Xu H, Sheng J, et al. Comparative evaluation of the effects of platelet-rich plasma formulations on extracellular matrix formation and the NF-κB signaling pathway in human articular chondrocytes[J]. Mol Med Rep, 2017, 15(5): 2940-2948.
[13]	Halpern B, Chaudhury S, Rodeo SA, et al. Clinical and MRI outcomes after platelet-rich plasma treatment for knee osteoarthritis[J]. Clin J Sport Med, 2013, 23(3): 238-239.
[14]	Görmeli G, Görmeli CA, Ataoglu B, et al. Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis: a randomized, double-blind, placebo-controlled trial[J]. Knee Surg Sports Traumatol Arthrosc, 2017, 25(3): 958-965.
[15]	Camurcu Y, Sofu H, Ucpunar H, et al. Single-dose intra-articular corticosteroid injection prior to platelet-rich plasma injection resulted in better clinical outcomes in patients with knee osteoarthritis: A pilot study[J]. J Back Musculoskelet Rehabil, 2018, 31(4): 603-610.
[16]	Ye Y, Zhou X, Mao S, et al. Comments on platelet-rich plasma versus hyaluronic acid in patients with hip osteoarthritis: A meta-analysis of randomized controlled trials[J]. Int J Surg, 2018, 53: 279-287.
[17]	Zhang HF, Wang CG, Li H, et al. Intra-articular platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis[J]. Drug Des Devel Ther, 2018, 5(12): 445-453.
[18]	Lana JF, Weglein A, Sampson SE, et al. Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee[J]. J Stem Cells Regen Med, 2016, 12(2): 6978.
[19]	Riboh JC, Saltzman BM, Yanke AB, et al. Effect of Leukocyte Concentration on the Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis[J]. Am J Sports Med, 2016, 44(3): 792-800.
[20]	Burmester GR, Pope JE. Novel treatment strategies in rheumatoid arthritis[J]. Lancet, 2017, 389(10086): 2338-2348.
[21]	Tong S, Liu J, Zhang C. Platelet-rich plasma inhibits inflammatory factors and represses rheumatoid fibroblast-like synoviocytes in rheumatoid arthritis[J]. Clin Exp Med, 2017, 17(4): 441-449.
[22]	Yan S, Yang B, Shang C, et al. Platelet-rich plasma promotes the migration and invasion of synovial fibroblasts in patients with rheumatoid arthritis[J]. Mol Med Rep, 2016, 14(3): 2269-2275.
[23]	Sebastian L, Bjoern M, Holger H, et al. Intraarticular Injection of Platelet-Rich Plasma Reduces Inflammation in a Pig Model of Rheumatoid Arthritis of the Knee Joint[J]. Arthritis Rheum, 2011, 63(11): 3344-3353.
[24]	Tong S, Zhang C, Liu J, et al. Platelet-rich plasma exhibits beneficial effects for rheumatoid arthritis mice by suppressing inflammatory factors[J]. Mol Med Rep, 2017, 16(4): 4082-4088.
[25]	Avila MY. Restoration of human lacrimal function following platelet-rich plasma injection[J]. Cornea, 2014, 33(1): 18-21.
[26]	Avila MY, Igua AM, Mora AM. Randomised, prospective clinical trial of platelet-rich plasma injection in the management of severe dry eye[J]. Br J Ophthalmol, 2018.
[27]	Virzì F, Bianca P, Giammona A, et al. Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients[J]. Stem Cell Research & Therapy, 2017, 8(1): 236.
[28]	Kanemaru H, Kajihara I, Yamanaka K, et al. Platelet-rich plasma therapy is eff ective for the treatment of refractory skin ulcers in patients with systemic sclerosis[J]. Mod Rheumatol, 2015, 25(4): 660-661.
[29]	Shetty S, Shenoi SD. Autologous platelet-rich fibrin in treatment of scleroderma ulcer[J]. Int Wound J, 2016, 13(5): 1065-1066.
[30]	Rallis E, Falidas E, Villias C. Amyopathic dermatomyositis-associated bilateral elbow ulcers successfully treated with autologous platelet-rich plasma[J]. Int J Dermatol, 2014, 53(1): 150-152.
[31]	Sriram S, Sankaralingam R, Mani M, et al. Autologous platelet rich plasma in the management of non-healing vasculitic ulcers[J]. Int J Rheum Dis, 2016, 19(12): 1331-1336.
[32]	艾智华，万勇，刘君静，等. 自体富血小板凝胶治疗痛风石合并慢性溃疡的疗效观察[J]. 四川大学学报(医学版), 2015, 46(5): 770-772.

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