Structural characteristics of fibronectin 1-5FNⅠ and its clinical application in the repair of peripheral nerve injury

doi:10.3877/cma.j.issn.1673-9450.2024.01.017

Abstract

Abstract:

Fibronectin type I structural module 1-5 (^1-5FNⅠ) has a variety of extracellular matrix molecule recognition and binding sites, and plays a role in physiological processes, such as cell adhesion and migration. In this paper, the position and structure of ^1-5FNⅠ and its interaction with extracellular matrix molecules are reviewed, and the application prospect of ^1-5FNⅠ in the repair and regeneration of peripheral nerve injury is discussed.

Key words: Fibronectin type I structural module 1-5, Binding sites, Integrins, Peripheral nerve injuries

Xiaoxu Liu, Chenyuan Yang, Shuzheng Wen, Jihong Wang, He Teng, Shangfei Jing. Structural characteristics of fibronectin ^1-5FNⅠ and its clinical application in the repair of peripheral nerve injury[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2024, 19(01): 87-91.

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