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中华损伤与修复杂志(电子版)

中华损伤与修复杂志(电子版) ›› 2020, Vol. 15 ›› Issue (06) : 495 -498. doi: 10.3877/cma.j.issn.1673-9450.2020.06.013

所属专题： 总编推荐； 文献；

综述

间充质干细胞在烧伤创面修复中的研究进展
王宏宇1, 刘玲英2, 巴特3,†()   
  1. 1. 010059　呼和浩特，内蒙古医科大学；014010　包头，内蒙古包钢医院烧伤科，烧伤医学研究所
    2. 100048　北京，解放军总医院第四医学中心烧伤整形科
    3. 014010　包头，内蒙古包钢医院烧伤科，烧伤医学研究所
  • 收稿日期:2020-10-27 出版日期:2020-12-01
  • 通信作者: 巴特
  • 基金资助:
    国家自然科学基金青年项目(81701900); 解放军总医院科技创新苗圃基金项目(17KMM28); 解放军总医院扶持基金项目(2017FC-304M-CXYY-01); 解放军总医院转化医学项目(2017TM-029); 内蒙古自治区自然科学基金项目(2015MS0815，2020MS08022); 内蒙古医科大学科技百万工程（联合）项目(YKD2016KJBW（LH）041)

Advances in the study of mesenchymal stem cells in burn wound repair

Hongyu Wang1, Lingying Liu2, Te Ba3,†()   

  1. 1. Inner Mongolia Medical University, Huhhot 010059, China; Department of Burns, Institute of Burns Medicine, Inner Mongolia BaoGang Hospital, Baotou 014010, China
    2. Department of Burns and Plastic Surgery, Fourth Medical Center of PLA General Hospital, Beijing 100048, China
    3. Department of Burns, Institute of Burns Medicine, Inner Mongolia BaoGang Hospital, Baotou 014010, China
  • Received:2020-10-27 Published:2020-12-01
  • Corresponding author: Te Ba
  • About author:
    Corresponding author: Ba Te, Email:
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王宏宇, 刘玲英, 巴特. 间充质干细胞在烧伤创面修复中的研究进展[J]. 中华损伤与修复杂志(电子版), 2020, 15(06): 495-498.

Hongyu Wang, Lingying Liu, Te Ba. Advances in the study of mesenchymal stem cells in burn wound repair[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2020, 15(06): 495-498.

烧伤是皮肤软组织损伤较常见的病因，给患者带来极大的生理及心理负担。目前临床上对大面积烧伤的救治仍有较大的局限性。近年来，关于干细胞治疗皮肤烧伤创面的组织工程研究备受关注。本文归纳、总结间充质干细胞治疗烧伤创面的临床前研究和临床试验性研究，并对MSC应用于烧伤创面修复的研究进展作一综述。

关键词: 烧伤, 伤口愈合, 间质干细胞, 组织工程

Burn is a common cause of skin and soft tissue injury, which brings great physiological and psychological burden to patients. Currently, there are still great limitations in the treatment of large area burn in clinical practice. In recent years, tissue engineering research on stem cell therapy for skin burn wounds has attracted much attention. In this paper, preclinical and experimental studies on the treatment of burn wounds by mesenchymal stem cell (MSC) were summarized, and the research progress on the application of MSC in burn wound repair was reviewed.

Key words: Burns, Wound healing, Mesenchymal stem cells, Tissue engineering
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