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中华损伤与修复杂志(电子版) ›› 2026, Vol. 21 ›› Issue (01) : 63 -68. doi: 10.3877/cma.j.issn.1673-9450.2026.01.011

综述

益生菌在烧伤创面愈合中作用机制的研究进展
陈强1, 曹胜军1, 李全1, 赵翠娟2,()   
  1. 1 014000 包头,内蒙古包钢医院(内蒙古医科大学第三临床医学院)烧伤外科
    2 014000 包头,内蒙古包钢医院(内蒙古医科大学第三临床医学院)消化内科
  • 收稿日期:2025-11-19 出版日期:2026-02-01
  • 通信作者: 赵翠娟
  • 基金资助:
    内蒙古自治区自然科学基金(2025MS08147); 内蒙古医学科学院公立医院科研联合基金科技项目(2024GLLH0687)

Research progress on the mechanism of action of probiotics in burn wound healing

Qiang Chen1, Shengjun Cao1, Quan Li1, Cuijuan Zhao2,()   

  1. 1 Department of Burn Surgery, Inner Mongolia Baogang Hospital (Third Clinical College of Inner Mongolia Medical University), Baotou 014000, China
    2 Department of Gastroenterology, Inner Mongolia Baogang Hospital (Third Clinical College of Inner Mongolia Medical University), Baotou 014000, China
  • Received:2025-11-19 Published:2026-02-01
  • Corresponding author: Cuijuan Zhao
引用本文:

陈强, 曹胜军, 李全, 赵翠娟. 益生菌在烧伤创面愈合中作用机制的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(01): 63-68.

Qiang Chen, Shengjun Cao, Quan Li, Cuijuan Zhao. Research progress on the mechanism of action of probiotics in burn wound healing[J/OL]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2026, 21(01): 63-68.

烧伤创面愈合过程复杂,存在微生物定植与愈合延迟等棘手问题,因此探索能够加速创面愈合、调控局部微环境的新型治疗策略至关重要。益生菌作为有益微生物,可通过抵抗致病菌、促进组织再生及免疫调节等机制促进创面愈合。目前研究表明,益生菌制剂在烧伤创面愈合中也显示出良好的应用前景。因此,有必要探讨烧伤创面菌群组成的变化、益生菌在创面愈合中的作用与机制,并对现有临床证据进行梳理,以期为改善烧伤患者创面愈合及生活质量提供方向性建议。

The healing process of burn wounds is intricate and often complicated by challenging issues such as microbial colonization and delayed healing. Thus, there is a critical need to explore novel therapeutic strategies that can accelerate wound healing and modulate the local microenvironment. As such agents, probiotics are beneficial microorganisms that exert effects including inhibiting pathogenic bacteria, promoting tissue regeneration, and modulating immune responses, thereby facilitating wound healing. Growing evidence has demonstrated that probiotic formulations hold promising potential for burn wound management. This article explores changes in burn wound microbiota composition and the role of probiotics in wound healing, by reviewing existing clinical evidence to offer insights and directions for improving outcomes and quality of life in burn patients.

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