Research progress of pretreated mesenchymal stem cell for wound healing

doi:10.3877/cma.j.issn.1673-9450.2018.06.015

Abstract

Abstract:

The incidence of various acute and chronic wounds is high, which brings great burden to patients and medical resources. Stem cell therapy is widely used in clinical research and can effectively repair injured tissue after transplantation. The survival rate of stem cells after transplantation is low due to the influence of infection, hypoxia, inflammatory factors and other factors, so it is unable to effectively homing to the injured tissue. Therefore, increasing the efficiency of stem cells in vivo plays an important role in promoting wound repair. Pretreatment of stem cells can change the biological activity of cells, which is the best strategy to improve the tolerance and homing ability of stem cells in microenvironment. This article reviews the progress of pretreated mesenchymal stem cell in promoting wound healing.

Key words: Mesenchymal stem cells, Wound healing, Pretreatment, Homing

Qiong Wang, Lingying Liu, Te Ba, Biao Zhou. Research progress of pretreated mesenchymal stem cell for wound healing[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2018, 13(06): 469-472.

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