Research progress on the effect of neutrophil extracellular traps in wound healing

doi:10.3877/cma.j.issn.1673-9450.2022.01.016

Abstract

Abstract:

Wound healing is closely related to immunity and inflammation. As one of the main effector cells of inflammation, neutrophils have been proved to play an important role in the pathophysiological process of diabetic foot and other types of wound healing. Recent studies have proven that neutrophils can inhibit or hinder wound healing by releasing neutrophil extracellular trap(NET) under the stimulation of inflammation and injury, and play an important role in the process of wound healing. However, the role of NET in different types of wound healing has not been fully elucidated. This article will focus on the latest research progress of immune response and inflammatory response in wound healing, combined with the role of NET in the wound healing of different types to make a review.

Key words: Wound healing, Wounds and injuries, Inflammation, Neutrophil extracellular traps, Neutrophil

Bin Cheng, Xixin Wu, Tian Xie. Research progress on the effect of neutrophil extracellular traps in wound healing[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(01): 85-88.

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