To explore the suitable wound treatment of diabetic foot for individual patient.

Two hundred and sixteen patients, with diabetic foot wounds, admitted in Beijing Jishuitan Hospital from Oct 1997 to Dec 2014, were performed personalized treatment according to given situation, except for following the principle of controlling blood sugar and infection.

Of all the patients, 1 case died of multiple organ failure, 2 wounds were recovered through lower limb amputation(including 1 case of bony infection and necrosis postoperative), 45 wounds were repaired with filleted flaps after the infective toes amputation. Fourteen cases were treated with debridement and vacuum sealing drainage(3 wounds were sutured directly, 11 cases were healed with skin graft), 97 cases were repaired through debridement, dressing change and sequential skin graft, 13 wounds were reconstructed by flap transplantation, 44 cases were healed by dressing change after wound debridement.

Diabetic foot was one of the most serious complications of diabetes mellitus, the ideal management should differ from patient to patient and wound to wound, the individualized treatment had to be tailor-made for the given situation.