Second-degree burns are a common type of burn in clinical practice. Currently, multiple types of dressings and topical medications can promote the healing of second-degree burn wounds. Among these, growth factors play a synergistic role in the wound healing process by promoting cell proliferation， migration， and differentiation， as well as enhancing angiogenesis and collagen synthesis. Although growth factor preparations have been used in clinical practice for many years， the emergence of new types and formulations of growth factors led to more prominent related controversies. How to select appropriate growth factors and apply timely and effectively for the treatment of burn wounds is a challenge in clinical application. This article compiles the consensus reached by experts in the field of burns and related areas on the use of growth factors for second-degree burn wounds， including the types， application scope， usage duration， and scar prevention， aiming to provide guiding recommendations for the use of growth factors in the treatment of second-degree burn wounds.