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中华损伤与修复杂志(电子版) ›› 2022, Vol. 17 ›› Issue (05) : 445 -449. doi: 10.3877/cma.j.issn.1673-9450.2022.05.012

综述

慢性创面伴自身免疫性疾病的研究进展
张苗苗1, 付倩倩2, 赵雅玫1, 余小平3, 周军利3,()   
  1. 1. 730000 兰州,甘肃中医药大学第一临床医学院
    2. 750000 银川,宁夏医科大学临床医学院
    3. 730000 兰州,甘肃省人民医院烧伤科
  • 收稿日期:2022-07-26 出版日期:2022-10-01
  • 通信作者: 周军利
  • 基金资助:
    甘肃省烧伤与创面修复临床医学研究中心(21JR7RA674); 甘肃省人民医院院内科研基金项目(21GSSYB-26)

Research progress of chronic wounds with autoimmune diseases

Miaomiao Zhang1, Qianqian Fu2, Yamei Zhao1, Xiaoping Yu3, Junli Zhou3,()   

  1. 1. First School of Clinical Medical, Gansu University of Chinese Medicine, Lanzhou 730000, China
    2. Clinical Medical School, Ningxia Medical University, Yinchuan 750000, China
    3. Department of Burn, Gansu Provincial Hospital, Lanzhou 730000, China
  • Received:2022-07-26 Published:2022-10-01
  • Corresponding author: Junli Zhou
引用本文:

张苗苗, 付倩倩, 赵雅玫, 余小平, 周军利. 慢性创面伴自身免疫性疾病的研究进展[J]. 中华损伤与修复杂志(电子版), 2022, 17(05): 445-449.

Miaomiao Zhang, Qianqian Fu, Yamei Zhao, Xiaoping Yu, Junli Zhou. Research progress of chronic wounds with autoimmune diseases[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2022, 17(05): 445-449.

自身免疫性疾病是由于自身产生抗体导致机体免疫耐受失衡,引起一系列慢性炎症反应,造成组织损伤的一类疾病。若并发皮肤溃疡,因其自身免疫因素及治疗药物等因素可能导致创面延迟愈合甚至无法愈合,因此,该类创面治疗难度较大,往往需要多学科医师联合诊疗。本文就慢性难愈创面伴自身免疫性疾病的发病机制、临床特点及疾病诊治做一系统综述,以期为自身免疫性疾病相关皮肤溃疡的诊治提供新见解。

Autoimmune disease is a kind of disease caused by the imbalance of immune tolerance caused by self-produced antibodies, which causes a series of chronic inflammatory reactions and tissue damage. If skin ulcer is complicated, the wound healing may be delayed or even unable to heal due to factors such as autoimmune factors and therapeutic drugs. Therefore, the treatment of such wounds is difficult, which often requires the joint diagnosis and treatment of multidisciplinary physicians. This article systematically reviews the pathogenesis, clinical characteristics, diagnosis and treatment of chronic refractory wounds with autoimmune diseases, in order to provide new insights for the diagnosis and treatment of autoimmune disease related skin ulcers.

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