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Chinese Journal of Injury Repair and Wound Healing(Electronic Edition) ›› 2019, Vol. 14 ›› Issue (05): 374-379. doi: 10.3877/cma.j.issn.1673-9450.2019.05.011

Special Issue:

• Review • Previous Articles     Next Articles

Diagnosis and treatment of necrotic soft tissue infection

Yingshu Cui1, Yi Li1, Zhanzhan Dai2, Xingfeng Zheng2,(), Zhaofan Xia2   

  1. 1. Basic Medical College, Naval Medical University, Shanghai 200433, China
    2. First Affiliated Hospital, Naval Medical University, Shanghai 200433, China
  • Received:2019-08-25 Online:2019-10-01 Published:2019-10-01
  • Contact: Xingfeng Zheng
  • About author:
    Corresponding author: Zheng Xingfeng, Email:

Abstract:

Necrotizing soft tissue infection (NSTI) is a kind of disease characterized by skin and subcutaneous soft tissue necrosis caused by bacterial infection. Firstly, the epidemiology, etiology and pathogenesis of NSTI are discussed in this paper and its major pathogenic microorganisms and classification are also summarized. Knowing the characteristics of rapid progress and serious local tissue destruction of NSTI, then we mainly describe the clinical manifestations and analyze the key points of diagnosis of NSTI in order to improve the alertness of clinicians to this kind of disease. Finally, this paper summarizes the current strategies for NSTI treatment, including thorough debridement and drainage, adequate resuscitation and the use of sensitive antibiotics.

Key words: Skin, Soft tissue infections, Fasciitis, necrotizing

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