Research progress of exosomes derived from different mesenchymal stem cells in skin wound repair

doi:10.3877/cma.j.issn.1673-9450.2021.06.010

Abstract

Abstract:

Exosomes are lipid bilayer vesicles secreted by a variety of tissues and cells, which contain proteins, lipids, mRNAs and other biological active components. Exosomes have the role of mediating the transfer of substances between cells and the exchange of information to regulate the biologically functions of cells. Studies have shown that exosomes derived from different mesenchymal stem cells can promote wound healing and inhibit scar formation by regulating multiple stages of the inflammatory response, cell proliferation and migration, angiogenesis, collagen deposition and other stages in skin wound healing. In this paper, the research progress of exosomes derived from different mesenchymal stem cells in skin wound is reviewed.

Key words: Exosomes, Mesenchymal stem cells, Wounds and injuries, Wound healing

Man Li, Wei Zhu, Haiping Zhang. Research progress of exosomes derived from different mesenchymal stem cells in skin wound repair[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2021, 16(06): 515-519.

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