Research progress of biomaterials for intervertebral disc regeneration and repair

doi:10.3877/cma.j.issn.1673-9450.2018.02.016

Abstract

Abstract:

Intervertebral disc degeneration is one of the main causes of low back pain. However, there are obvious limitations of the traditional conservative treatment and surgical treatment. The development of intervertebral disc tissue engineering technology provides a new treatment option for intervertebral disc degeneration. As a key process in the construction of tissue engineered intervertebral disc, scaffold material is the focus and difficulty. At present, the common materials include natural materials, biologically based materials and synthetic polymers materials. This review focuses on the materials of annulus fibrosus, nucleus pulposus and complete intervertebral disc. While this field still in early development, bioengineering-based strategies employing novel biomaterials are emerging as promising alternatives for clinical treatment of intervertebral disc disorders.

Key words: Intervertebral disc, Tissue engineering, Stents, Intervertebral disc degeneration

Feng Wang, Xinmin Feng, Liang Zhang, Yang Liu, Liping Nan, Shifeng Zhou. Research progress of biomaterials for intervertebral disc regeneration and repair[J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2018, 13(02): 146-150.

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URL: https://zhssyxfzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1673-9450.2018.02.016

https://zhssyxfzz.cma-cmc.com.cn/EN/Y2018/V13/I02/146

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